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NCT04792710
Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection
Phase 4 trial testing Metronidazole in Prevention of Postpartum Sepsis in 1,000 participants. Status unknown.
31 March 2022
Quick facts
| Lead sponsor | University of Pretoria |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 1,000 |
| Start date | 8 March 2021 |
| Primary completion | 31 March 2022 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across South Africa |
Drugs / interventions tested
- Metronidazole (METRONIDAZOLE) — full drug profile →
Conditions studied
- Prevention of Postpartum Sepsis — all drugs for Prevention of Postpartum Sepsis →
Sponsor
University of Pretoria
Who can join
18 and older, female only, with Prevention of Postpartum Sepsis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Randomised controlled trial to investigate the efficacy of adding metronidazole pre-operatively to kefazolin in reducing postpartum infection
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04792710
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Pretoria trials
Trials by the same sponsor.
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- NCT05632705 — Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis · NA · completed
- NCT02750202 — Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts · Phase 3 · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04792710 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pretoria
- Last refreshed: 11 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04792710.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing