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NCT04791995: ReCapp

Resuscitation and Capillary Reperfusion

Completed Last updated 26 September 2022
What this trial tests

trial in Cardiac Arrest in 50 participants. Completed in 1 May 2022.

Timeline
3 March 2021
Primary endpoint
31 March 2022
1 May 2022

Quick facts

Lead sponsorMedical University of Vienna
StatusCompleted
Study typeOBSERVATIONAL
Enrollment50
Start date3 March 2021
Primary completion31 March 2022
Estimated completion1 May 2022
Sites1 location across Austria

Conditions studied

Sponsor

Medical University of Vienna

Who can join

Adults 18 to 95, any sex, with Cardiac Arrest or Cardiac Arrest, Out-Of-Hospital. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Persistent microperfusion alterations after return of spontaneous circulation (ROSC) are associated with poor survival. To our knowledge, no human studies evaluating microperfusion during cardiopulmonary resuscitation (CPR) with simple and pre-hospital available tests have been published. Capillary refill time (CRT) and skin-mottling-score (SMS) are parameters for microperfusion and evaluated in septic and cardiogenic shock. In animal studies, microperfusion was impaired during cardiac arrest, although not correlating with systemic blood pressure. The aim of this study is to investigate the correlation between impaired microcirculation (as measured with CRT and SMS) during resuscitation and ROSC resp. neurological outcome. Our clinical impression in daily routine is, that the appearance of a patient undergoing CPR is often linked to the outcome. We hypothesize, that this is due to changes in microperfusion of the skin.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The association of capillary refill time and return of spontaneous circulation during out-of-hospital cardiac arrest: an observational study.
    Mueller M, Holzer M, Losert H, Grassmann D, et al · · 2025 · PMID 39838473 · DOI 10.1186/s13054-025-05255-4

Verify or expand the search:

Other recruiting trials for Cardiac Arrest

Currently open trials in the same condition.

Other Medical University of Vienna trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04791995.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing