Last reviewed · How we verify
NCT04789473
OneinSeven Gestational Diabetes Genetic and Socioeconomic Risk Study
trial testing Polygenic Risk Score Generation in Gestational Diabetes in 10,000 participants. Status unknown.
1 April 2022
Quick facts
| Lead sponsor | Prenome |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 10,000 |
| Start date | 24 June 2021 |
| Primary completion | 1 April 2022 |
| Estimated completion | 1 August 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Polygenic Risk Score Generation
Conditions studied
- Gestational Diabetes — all drugs for Gestational Diabetes →
- Pregnancy Complications — all drugs for Pregnancy Complications →
- Pregnancy Related — all drugs for Pregnancy Related →
- Genetic Predisposition — all drugs for Genetic Predisposition →
Sponsor
Prenome
Who can join
18 and older, female only, with Gestational Diabetes or Pregnancy Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of the Gestational Diabetes Genetic Socioeconomic Risk Study is to generate genome wide association study data (GWAS) to calculate polygenic risk scores (PRS) for the development of gestational diabetes in pregnant women. Oshun Medical's GWAS study will be conducted by collecting DNA samples alongside medical and socioeconomic data and applying data science methodology to generate a polygenic risk score algorithm for gestational diabetes. Our hypothesis is that key genetic variants linked to gestational diabetes will be identified, and sociodemographic characteristics may impact epigenetic factors which further contribute to this risk of gestational diabetes. The PRS generated through our study will be combined with an analysis of epigenetic factors to produce a new method for predicting risk of developing gestational diabetes during pregnancy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04789473
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT07174245 — Pregnancy and Postpartum CGM in GDM · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04789473 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Prenome
- Last refreshed: 30 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04789473.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing