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NCT04782765
Phase Ⅱ Trial of Camrelizumab in Patients Without Distant Metastasis Nasopharyngeal Carcinoma
Phase 2 trial testing Camrelizumab+Chemotherapy+Chemoradiotherapy in Disease-free Survival Rate in 59 participants. Status unknown.
20 March 2023
Quick facts
| Lead sponsor | Tianjin Medical University Cancer Institute and Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 59 |
| Start date | 20 March 2021 |
| Primary completion | 20 March 2023 |
| Estimated completion | 20 March 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Camrelizumab+Chemotherapy+Chemoradiotherapy — full drug profile →
Conditions studied
- Disease-free Survival Rate — all drugs for Disease-free Survival Rate →
Sponsor
Tianjin Medical University Cancer Institute and Hospital
Who can join
Under 70, any sex, with Disease-free Survival Rate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To see the effect if a combination of neoadjuvant chemotherapy combined with Camrelizumab followed by chemoradiotherapy in treating patients without distant metastasis nasopharyngeal carcinoma
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes.
Liu H, Tang L, Li Y, Xie W, et al · · 2024 · cited 85× · PMID 38254110 · DOI 10.1186/s12943-023-01928-2 -
Current status and advances of immunotherapy in nasopharyngeal carcinoma.
Xu JY, Wei XL, Wang YQ, Wang FH. · · 2022 · cited 62× · PMID 35547095 · DOI 10.1177/17588359221096214 -
Precision medicine in nasopharyngeal carcinoma: comprehensive review of past, present, and future prospect.
Siak PY, Heng WS, Teoh SSH, Lwin YY, et al · · 2023 · cited 33× · PMID 37932756 · DOI 10.1186/s12967-023-04673-8 -
Advance in integrating platinum-based chemotherapy with radiotherapy for locally advanced nasopharyngeal carcinoma.
Zhu F, Wu Y, Wang H. · · 2023 · cited 9× · PMID 37860184 · DOI 10.3389/fonc.2023.1259331 -
Induction chemotherapy plus camrelizumab combined with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma in non-endemic areas: a phase 2 clinical trial in North China.
Wang Z, Sun Y, Wang Q, Chai Y, et al · · 2025 · cited 5× · PMID 40016735 · DOI 10.1186/s12916-025-03964-9 -
A Systematic Review and Meta-Analysis of Studies Comparing Concurrent Chemoradiotherapy With Radiotherapy Alone in the Treatment of Stage II Nasopharyngeal Carcinoma.
Xu YC, Chen KH, Liang ZG, Zhu XD. · · 2022 · cited 2× · PMID 35903695 · DOI 10.3389/fonc.2022.843675
Verify or expand the search:
- PubMed search for NCT04782765
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04782765 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tianjin Medical University Cancer Institute and Hospital
- Last refreshed: 4 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04782765.
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