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NCT04782531: RESPIFLUX
Variations of Portal Flow During the Respiratory Cycle in Healthy Volunteers
NA trial testing peripheral ECG in Respiratory Amplitude in 22 participants. Completed in 7 October 2024.
1 March 2023
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire, Amiens |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 22 |
| Start date | 1 March 2021 |
| Primary completion | 1 March 2023 |
| Estimated completion | 7 October 2024 |
| Sites | 1 location across France |
Drugs / interventions tested
- peripheral ECG
- Standard MRI
Conditions studied
- Respiratory Amplitude — all drugs for Respiratory Amplitude →
- Portal Blood Flow — all drugs for Portal Blood Flow →
- MRI — all drugs for MRI →
- Echo Planar Imaging — all drugs for Echo Planar Imaging →
Sponsor
Centre Hospitalier Universitaire, Amiens
Who can join
18 and older, any sex, with Respiratory Amplitude or Portal Blood Flow. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The analysis of portal vein blood flow is important when assessing the severity and progression of liver disease. It is important to understand normal liver regulation in order to appreciate the evaluation of the effect of treatment during the disease progression. The influence of respiration on hepatic hemodynamics is still poorly understood, although some studies have shown a significant impact. The purpose of this project is to quantify the blood flow variations in the portal vein at different positions during the respiratory cycle by using a fast MRI sequence and an Echo Planar (EPI) acquisition.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04782531
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04782531 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire, Amiens
- Last refreshed: 29 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04782531.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing