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NCT04778306
Transoral Laser Surgery and Radiotheraphy for Early Stage Laryngeal Squamous Cell Cancer
NA trial testing Transoral Laser Surgery in Larynx Cancer in 261 participants. Completed in 31 December 2019.
31 December 2019
Quick facts
| Lead sponsor | Saglik Bilimleri Universitesi |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 261 |
| Start date | 1 January 2010 |
| Primary completion | 31 December 2019 |
| Estimated completion | 31 December 2019 |
Drugs / interventions tested
- Transoral Laser Surgery
Conditions studied
- Larynx Cancer — all drugs for Larynx Cancer →
Sponsor
Saglik Bilimleri Universitesi — full company profile →
Who can join
Adults 33 to 83, any sex, with Larynx Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: The investigators aimed to compare the oncological results of patients with early stage laryngeal squamous cell carcinoma (LSCC) treated with Transoral Laryngeal Surgery (TOLS) and Radiotheraphy (RT). Methods: The patients were divided into two groups as TOLS (Group 1) and RT (Group 2) according to the treatment method. Both groups were compared with each other in terms of local recurrence, regional recurrence, distant metastasis, 3 and 5-year overall survival, disease-free survival, disease-specific survival and laryngectomy-free survival rates. Survival analyses was made by Kaplan Meier product limit estimation. A p-value of less than 0.05 was considered as statistically significant.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparisons of the oncological results of transoral laser surgery and radiotherapy for early stage laryngeal squamous cell cancer: single-center long-term results.
Doluoglu S, Bayir O, Ocal B, Tatar EC, et al · · 2024 · cited 2× · PMID 39127898 · DOI 10.5144/0256-4947.2024.213
Verify or expand the search:
- PubMed search for NCT04778306
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Larynx Cancer
Currently open trials in the same condition.
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- NCT06039631 — Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer · Phase 2 · recruiting
- NCT05337631 — Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy · recruiting
- NCT04368702 — CONFIRM: Magnetic Resonance Guided Radiation Therapy · NA · recruiting
Other Saglik Bilimleri Universitesi trials
Trials by the same sponsor.
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- NCT07344649 — Turkish Validation of the Nijmegen Questionnaire in COPD · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04778306 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi
- Last refreshed: 3 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04778306.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing