NCT04771975: C4E

Connecting Breast Cancer Survivors for Exercise

Completed NA Last updated 21 August 2023

What this trial tests

NA trial testing Exercise Counselling in Breast Cancer in 108 participants. Completed in 30 January 2022.

Timeline

10 May 2021

Primary endpoint
30 December 2021

30 January 2022

Quick facts

Lead sponsor	Jenna Smith
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	108
Start date	10 May 2021
Primary completion	30 December 2021
Estimated completion	30 January 2022
Sites	1 location across Canada

Drugs / interventions tested

• Exercise Counselling
• Partner Matching
• Resistance training sessions led by a QEP

Conditions studied

• Breast Cancer — all drugs for Breast Cancer →
• Breast Neoplasms — all drugs for Breast Neoplasms →

Sponsor

Jenna Smith

Who can join

18 and older, female only, with Breast Cancer or Breast Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Phase 1: The purpose of this study is to examine interpersonal and individual effects of partnering BCS with a peer and a qualified exercise professional (QEP) on self-reported exercise volume (MVPA; primary outcome), and device-measured exercise volume (MVPA; Fitbit), social support, and HRQOL (secondary outcomes). Cost-effectiveness and intervention adherence will also be explored as tertiary outcomes. The effects of a peer and QEP-support intervention group, labelled MatchQEP, will be compared to a control group of BCS who are matched with a peer, but not a QEP, labelled Match.

Phase 2: The purpose of this study is to examine whether the addition of 8-weekly QEP-lead resistance training Zoom sessions with an exercise partner interacts with social support (i.e., tangible, informational, emotional) and how this interaction relates to overall exercise volume as an extension of Phase 1 (one year after phase 1 was completed). A secondary aim of Phase 2 is to examine the direct influence of resistance training on body image, self-efficacy, the physical self, and body functionality among the participants.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

1. Connecting breast cancer survivors for exercise: protocol for a two-arm randomized controlled trial.
   Smith-Turchyn J, McCowan ME, O'Loughlin E, Fong AJ, et al · · 2021 · cited 8× · PMID 34649590 · DOI 10.1186/s13102-021-00341-w
2. Connecting women who are diagnosed and treated for breast cancer to engage in physical activity: a two-arm randomized controlled trial.
   Murray RM, O'Loughlin E, Smith-Turchyn J, Fong AJ, et al · · 2025 · cited 1× · PMID 40281585 · DOI 10.1186/s13102-025-01131-4
3. Resistance Training in Women Diagnosed with Breast Cancer: A Pilot Single Arm Pre-Post Intervention.
   Vani MF, Marashi M, O'Loughlin EK, Smith-Turchyn J, et al · · 2024 · cited 1× · PMID 39199600 · DOI 10.3390/cancers16162829
4. Connecting breast cancer survivors for exercise: protocol for a two-arm randomized controlled trial.
   Smith-Turchyn J, McCowan ME, O'Loughlin E, Fong AJ, et al · · 2021 · PMID 34664019 · DOI 10.1186/s13102-021-00341-w