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NCT04771767
Combined Ketamine and eCBT Intervention for PTSD
Status unknown
Phase 2
Last updated 11 August 2022
What this trial tests
Phase 2 trial testing Ketamine in Post-Traumatic Stress Disorder in 16 participants. Status unknown.
Timeline
1 August 2021
Primary endpoint
31 March 2024
31 March 2024
31 March 2024
Quick facts
| Lead sponsor | Queen's University |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 16 |
| Start date | 1 August 2021 |
| Primary completion | 31 March 2024 |
| Estimated completion | 31 March 2024 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Ketamine (ketamine) — full drug profile →
- Online Trauma-Focused Cognitive Behavioural Therapy
Conditions studied
- Post-Traumatic Stress Disorder — all drugs for Post-Traumatic Stress Disorder →
Sponsor
Queen's University
Who can join
Adults 18 to 65, any sex, with Post-Traumatic Stress Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
An open label RCT assessing the efficacy of a combined treatment approach for PTSD, using Ketamine infusions and online Cognitive Behavioural Therapy.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Alleviating anxiety and taming trauma: Novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder.
Singewald N, Sartori SB, Reif A, Holmes A. · · 2023 · cited 40× · PMID 36623804 · DOI 10.1016/j.neuropharm.2023.109418 -
Acute sleep interventions as an avenue for treatment of trauma-associated disorders.
Swift KM, Thomas CL, Balkin TJ, Lowery-Gionta EG, et al · · 2022 · cited 16× · PMID 35678060 · DOI 10.5664/jcsm.10074 -
The potential of ketamine for posttraumatic stress disorder: a review of clinical evidence.
Ragnhildstveit A, Roscoe J, Bass LC, Averill CL, et al · · 2023 · cited 13× · PMID 36895431 · DOI 10.1177/20451253231154125 -
Combining Ketamine and Internet-Based Cognitive Behavioral Therapy for the Treatment of Posttraumatic Stress Disorder: Protocol for a Randomized Controlled Trial.
Philipp-Muller AE, Reshetukha T, Vazquez G, Milev R, et al · · 2021 · cited 6× · PMID 34092549 · DOI 10.2196/30334
Verify or expand the search:
- PubMed search for NCT04771767
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
Data sources for this page
- Trial protocol + status: ClinicalTrials.gov NCT04771767 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Queen's University
- Last refreshed: 11 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04771767.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing