NCT04771585 (QUELLE) is a NA clinical trial of Community Mask in Healthy, sponsored by Fraunhofer-Institute of Toxicology and Experimental Medicine.

Who is sponsoring NCT04771585?

NCT04771585 is sponsored by Fraunhofer-Institute of Toxicology and Experimental Medicine.

What drugs are being tested in NCT04771585?

Interventions in NCT04771585: Community Mask, Surgical Mask, FFP2 respirator, FFP3 respirator.

Is NCT04771585 still recruiting?

NCT04771585 is currently completed. Last updated 26 August 2021.

Last reviewed 2021-08-26 · How we verify

NCT04771585: QUELLE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Quantification of Exhaled Particles to Identify Airborne Transmission Risks of COVID-19

Completed NA Last updated 26 August 2021

What this trial tests

NA trial testing Community Mask in Healthy in 30 participants. Completed in 20 August 2021.

Timeline

29 March 2021

Primary endpoint
20 August 2021

20 August 2021

Quick facts

Lead sponsor	Fraunhofer-Institute of Toxicology and Experimental Medicine
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	sequential
Masking	none
Primary purpose	basic science
Enrollment	30
Start date	29 March 2021
Primary completion	20 August 2021
Estimated completion	20 August 2021
Sites	1 location across Germany

Drugs / interventions tested

Community Mask
Surgical Mask
FFP2 respirator
FFP3 respirator

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Fraunhofer-Institute of Toxicology and Experimental Medicine

Who can join

Adults 18 to 80, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, the aerosols emitted during various respiratory activities will be quantified in healthy subjects. The differences in aerosol size spectrum and number during tidal breathing, speaking, coughing and singing will be assessed. Subjects with an endogenously high aerosol emission will repeat the respiratory activities wearing face masks with varying particle filter capacity to investigate the aerosol emission reduction.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Quantifying Exhaled Particles in Healthy Humans During Various Respiratory Activities Under Realistic Conditions.
Schwarz K, Struß N, Banari L, Hohlfeld JM. · · 2024 · PMID 38285475 · DOI 10.1089/jamp.2022.0076

Verify or expand the search:

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Other Fraunhofer-Institute of Toxicology and Experimental Medicine trials

Trials by the same sponsor.

NCT06035276 — Biosensor and Environmental Sensor Development Within the REMEDIA Project · NA · completed
NCT05346718 — Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis · NA · completed
NCT05245175 — Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions · NA · completed
NCT05019209 — Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients · NA · completed
NCT04914273 — Use of Exhaled Particles to Assess Lung Pharmacokinetics · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04771585 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fraunhofer-Institute of Toxicology and Experimental Medicine
Last refreshed: 26 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04771585.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing