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NCT04771156
Ketorolac in Palatoplasty
Phase 4 trial testing Ketorolac in Cleft Lip and Palate in 74 participants. Currently enrolling.
1 March 2027
Quick facts
| Lead sponsor | The University of Texas Health Science Center, Houston |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 74 |
| Start date | 17 September 2021 |
| Primary completion | 1 March 2027 |
| Estimated completion | 1 April 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ketorolac (KETOROLAC) — full drug profile →
- Placebo
Conditions studied
- Cleft Lip and Palate — all drugs for Cleft Lip and Palate →
Sponsor
The University of Texas Health Science Center, Houston
Who can join
6 Months and older, any sex, with Cleft Lip and Palate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to see if the addition of IV Ketorolac to usual care multi-modal pain therapy compared to usual care will improve oral intake post-operatively
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04771156
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ketorolac
Trials testing the same drug.
- NCT07487246 — Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement · Phase 2 · not yet recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT06994442 — Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · recruiting
- NCT06968806 — Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection · Phase 3 · recruiting
- NCT06973785 — Non-Narcotic Pain Control After ACL Reconstruction · Phase 3 · recruiting
Other recruiting trials for Cleft Lip and Palate
Currently open trials in the same condition.
- NCT06510881 — Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate · NA · recruiting
- NCT06284434 — Liposomal Bupivacaine Use in Alveolar Bone Graft Patients · Phase 3 · recruiting
- NCT06408337 — Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIOCLEFT in the Treatment of Cleft Palate. · Phase 1, PHASE2 · recruiting
- NCT06122805 — Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery · NA · recruiting
- NCT05796336 — Two Methods of Lip Taping as a Presurgical Orthopedic Appliance · NA · recruiting
Other The University of Texas Health Science Center, Houston trials
Trials by the same sponsor.
- NCT04200729 — Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-cente · Phase 4 · not yet recruiting
- NCT07225062 — Improving HIV Prevention and Substance Use Post-Sexual Assault Services · NA · not yet recruiting
- NCT07396974 — Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT) · NA · not yet recruiting
- NCT07170163 — Navigating the Transition to Adulthood: A Dual Language Mobile App for Latino Youth With ASD and Their Families · NA · not yet recruiting
- NCT06915441 — Lipid Infusions to Optimize Nutrition Trial · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04771156 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of Texas Health Science Center, Houston
- Last refreshed: 19 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04771156.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing