Last reviewed · How we verify

NCT04770090: CTC-COL

Research of Circulating Tumor Cells Released During Cervical Cancer Surgery

Completed NA Last updated 10 July 2025
What this trial tests

NA trial testing Blood samples in Cervical Cancer Stage IA1 in 200 participants. Completed in 22 August 2022.

Timeline
10 March 2022
Primary endpoint
22 August 2022
22 August 2022

Quick facts

Lead sponsorUniversity Hospital, Montpellier
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeprevention
Enrollment200
Start date10 March 2022
Primary completion22 August 2022
Estimated completion22 August 2022
Sites3 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Montpellier

Who can join

18 and older, female only, with Cervical Cancer Stage IA1 or Cervical Cancer Stage IB1. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cervical cancer is a rare pathology. Recent studies showed that the risk of recurrence is higher for patients treated by coelioscopy in comparison with laparotomy. It could be explained by the spread of circulating tumor cells (CTC) due to tumor mobilization during different steps of the surgery. The primary goal is to evaluate the spread of CTC during surgery on peripheral blood samples. The secondary outcome is to evaluation the disease-free survival at 3 and 5 years postoperatively. 20 patients with early stage cervical (IA1 to IB2) eligible to coelioscopic stadification and laparoscopic surgery will be included.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Redefining cancer care: harnessing circulating tumor cells' potential for improved diagnosis and prognosis.
    Janjua D, Chaudhary A, Joshi U, Tripathi T, et al · · 2025 · cited 4× · PMID 40676582 · DOI 10.1186/s12935-025-03883-y

Verify or expand the search:

Other trials of Blood samples

Trials testing the same drug.

Other University Hospital, Montpellier trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04770090.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing