Last reviewed · How we verify
NCT04770090: CTC-COL
Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
NA trial testing Blood samples in Cervical Cancer Stage IA1 in 200 participants. Completed in 22 August 2022.
22 August 2022
Quick facts
| Lead sponsor | University Hospital, Montpellier |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 200 |
| Start date | 10 March 2022 |
| Primary completion | 22 August 2022 |
| Estimated completion | 22 August 2022 |
| Sites | 3 locations across France |
Drugs / interventions tested
- Blood samples — full drug profile →
Conditions studied
- Cervical Cancer Stage IA1 — all drugs for Cervical Cancer Stage IA1 →
- Cervical Cancer Stage IB1 — all drugs for Cervical Cancer Stage IB1 →
- Cervical Cancer Stage IA2 — all drugs for Cervical Cancer Stage IA2 →
- Cervical Cancer Stage IB2 — all drugs for Cervical Cancer Stage IB2 →
Sponsor
University Hospital, Montpellier
Who can join
18 and older, female only, with Cervical Cancer Stage IA1 or Cervical Cancer Stage IB1. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cervical cancer is a rare pathology. Recent studies showed that the risk of recurrence is higher for patients treated by coelioscopy in comparison with laparotomy. It could be explained by the spread of circulating tumor cells (CTC) due to tumor mobilization during different steps of the surgery. The primary goal is to evaluate the spread of CTC during surgery on peripheral blood samples. The secondary outcome is to evaluation the disease-free survival at 3 and 5 years postoperatively. 20 patients with early stage cervical (IA1 to IB2) eligible to coelioscopic stadification and laparoscopic surgery will be included.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Redefining cancer care: harnessing circulating tumor cells' potential for improved diagnosis and prognosis.
Janjua D, Chaudhary A, Joshi U, Tripathi T, et al · · 2025 · cited 4× · PMID 40676582 · DOI 10.1186/s12935-025-03883-y
Verify or expand the search:
- PubMed search for NCT04770090
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04770090 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Montpellier
- Last refreshed: 10 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04770090.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing