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NCT04769622
Influence of Environmental Factors on the Efficacy of Non-surgical Periodontal Treatment. A Pre-post Quasi-experimental Study
trial testing Non-surgical periodontal treatment in Non Surgical Periodontal Treatment in 125 participants. Status unknown.
20 August 2021
Quick facts
| Lead sponsor | University of Siena |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 125 |
| Start date | 16 February 2021 |
| Primary completion | 20 August 2021 |
| Estimated completion | 25 November 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Non-surgical periodontal treatment
- Questionnaires
Conditions studied
- Non Surgical Periodontal Treatment — all drugs for Non Surgical Periodontal Treatment →
- Periodontitis — all drugs for Periodontitis →
- Periodontal Diseases — all drugs for Periodontal Diseases →
Sponsor
University of Siena
Who can join
Adults 18 to 70, any sex, with Non Surgical Periodontal Treatment or Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Periodontitis is a biofilm-mediated chronic inflammatory disease which causes the destruction of the supporting tissues of the tooth. Risk factors for periodontitis include familiarity for periodontal diseases, diabetes, cardiovascular diseases, metabolic syndrome, obesity and stress. Some studies demonstrated how these risk factors negatively influence the patients' response to non-surgical periodontal treatment. The success of non-surgical periodontal therapy is defined through the treat-to-target concept (i.e. a maximum of 4 sites with Probing Pocket Depth \>5mm and presence of Bleeding on Probing); therefore, periodontal treatment is successful whenever this threshold is reached. Moreover, given the available data regarding the association between more severe forms of periodontitis and a lower frequency of physical activity, a worse sleep quality and more perceived stress, it is reasonable to hypothesize that these factors could influence the patients' response to non-surgical periodontal treatment. With regards to diet, despite many studies appraised the anti-inflammatory effect of the mediterranean diet, no study has ever related adherence to Mediterranean Diet to oral health status. The novelty that the present study would introduce is the evaluation of how environmental factors (i.e. diet, physical exercise, perceived stress) influence patients' response to non-surgical periodontal therapy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04769622
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Other University of Siena trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04769622 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Siena
- Last refreshed: 24 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04769622.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing