NCT04768400 is a NA clinical trial of Arm I (MEP) in Brain Tumor, sponsored by Gangnam Severance Hospital.

Who is sponsoring NCT04768400?

NCT04768400 is sponsored by Gangnam Severance Hospital.

What drugs are being tested in NCT04768400?

Interventions in NCT04768400: Arm I (MEP).

What condition does NCT04768400 study?

NCT04768400 studies Brain Tumor.

Is NCT04768400 still recruiting?

NCT04768400 is currently completed. Last updated 6 June 2023.

Last reviewed 2023-06-06 · How we verify

NCT04768400

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MEP and Neuromuscular Blocker

Completed NA Last updated 6 June 2023

What this trial tests

NA trial testing Arm I (MEP) in Brain Tumor in 100 participants. Completed in 13 May 2022.

Timeline

9 March 2021

Primary endpoint
13 May 2022

13 May 2022

Quick facts

Lead sponsor	Gangnam Severance Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	100
Start date	9 March 2021
Primary completion	13 May 2022
Estimated completion	13 May 2022
Sites	1 location across South Korea

Drugs / interventions tested

Arm I (MEP) — full drug profile →

Conditions studied

Brain Tumor — all drugs for Brain Tumor →

Sponsor

Gangnam Severance Hospital

Who can join

19 and older, any sex, with Brain Tumor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is important to predict the influence of the neuromuscular blocking agents on the motor evoked potential. Investigator will investigate the dose-response relationship between the degree of the neuromuscular blockade and the motor evoked potential in patients undergoing brain tumor surgery using the population approach. Investigator will investigate the influence of the other factors such as the impedence, reactance, muscel amount, and age on the motor evoked potential.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Intraoperative glioblastoma surgery-current challenges and clinical trials: An update.
Patel V, Chavda V. · · 2024 · cited 14× · PMID 39371095 · DOI 10.1016/j.cpt.2023.11.006
Quantitative Analysis of the Effect of Neuromuscular Blockade on Motor-Evoked Potentials in Patients Undergoing Brain Tumor Removal Surgery: A Prospective, Single-Arm, Open-Label Observational Study.
Chae D, Kim HC, Park HH, Yoo J, et al · · 2024 · PMID 39124548 · DOI 10.3390/jcm13154281

Verify or expand the search:

Other recruiting trials for Brain Tumor

Currently open trials in the same condition.

NCT07224503 — C-SMART vs BE Well for Patients With Brain Tumors · NA · recruiting
NCT07323966 — Feasibility of Mask-Free Radiotherapy for Brain Tumor Patients · NA · recruiting
NCT07122752 — Feasibility and Outcomes of 3D-printed External Cranial Orthosis After Craniectomy · active not recruiting
NCT07105358 — Visual Plasticity Following Brain Lesions · NA · recruiting
NCT06810544 — Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss · Phase 1, PHASE2 · recruiting

Other Gangnam Severance Hospital trials

Trials by the same sponsor.

NCT07505628 — AI-based Rehabilitation for Hip and Knee Surgery Patients · NA · not yet recruiting
NCT07311122 — Endocrine Therapy Base on 21-gene RS · not yet recruiting
NCT07011823 — Immune-checkpoint Blockade After Partial Breast Irradiation by Pembrolizumab in Early TNBC · Phase 2 · not yet recruiting
NCT07211451 — Axillary Nodal Burden in HER2+ and TNBC · completed
NCT06839716 — Comparison of Ropivacaine-Poloxamer 407 Hydrogel and TAP Block for Postoperative Pain Management in Laparoscopic/Robotic · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04768400 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Gangnam Severance Hospital
Last refreshed: 6 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04768400.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing