NCT04766528: PerOME

Effect of Diet on the Microbiota / Endoccanabinoidome Axis in Response to Physical Activity

Completed NA Last updated 23 February 2021

What this trial tests

NA trial testing 3 maximal aerobic tests in Diet Habit in 11 participants. Completed in 14 November 2019.

Timeline

6 September 2019

Primary endpoint
14 November 2019

14 November 2019

Quick facts

Lead sponsor	Laval University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	basic science
Enrollment	11
Start date	6 September 2019
Primary completion	14 November 2019
Estimated completion	14 November 2019
Sites	1 location across Canada

Drugs / interventions tested

• 3 maximal aerobic tests

Conditions studied

• Diet Habit — all drugs for Diet Habit →
• Microbial Colonization — all drugs for Microbial Colonization →
• Activity, Motor — all drugs for Activity, Motor →

Sponsor

Laval University

Who can join

Adults 20 to 30, female only, with Diet Habit or Microbial Colonization. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Both the endocannabinoid system and the microbiome are highly conditioned by nutrition and physical activity, and have an interdependent, bidirectional relationship. We suggest studying the interleaving between the endocannabinoidome-microbiome axis and host metabolism under the combined effect of a diet and physical activity. More specificly, we will study the link between the impact of the diet on the intestinal microbiome and the endocannabinoid reaction after intense exercise.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Influence of diet on acute endocannabinoidome mediator levels post exercise in active women, a crossover randomized study.
   Forteza F, Bourdeau-Julien I, Nguyen GQ, Guevara Agudelo FA, et al · · 2022 · cited 18× · PMID 35595747 · DOI 10.1038/s41598-022-10757-0