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NCT04765189
Evaluation of Mangoselect® in Improvement of Exercise/Activity-induced Knee Joint Discomfort in Subjects Suffering From Osteoarthritis Grade I or II
NA trial testing Placebo in Osteoarthritis, Knee in 95 participants. Completed in 26 October 2023.
26 October 2023
Quick facts
| Lead sponsor | Fytexia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 95 |
| Start date | 1 March 2021 |
| Primary completion | 26 October 2023 |
| Estimated completion | 26 October 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Placebo
- Verum A
- Verum B
- Verum C
Conditions studied
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Sponsor
Fytexia
Who can join
Adults 50 to 75, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the present investigation is to evaluate the efficacy of Mangoselect®, a mangosteen extract, and of a formulation containing Mangoselect®, in subjects suffering from activity/exercise-induced knee joint pain/discomfort, during a 12-week supplementation period. Subjective discomfort improvement will be assessed with both WOMAC questionnaire and pain Visual Analogic Scale (VAS); functional joints features, quality of life, and inflammatory markers, will also be assessed. Finally, long lasting benefits will additionally be evaluated 4 weeks after the end of the supplementation period. The design of the study is double-blind, randomized, multi-arm, parallel and placebo controlled.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04765189
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Verum A
Trials testing the same drug.
- NCT05926947 — OXXYNEA® GS: Study for Glycaemia Management · NA · active not recruiting
Other recruiting trials for Osteoarthritis, Knee
Currently open trials in the same condition.
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
- NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
- NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
- NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting
Other Fytexia trials
Trials by the same sponsor.
- NCT06949592 — Oral Bioavailability of the Phenolic Compounds in a Melissa Supplement · NA · completed
- NCT06062511 — Poplar-type Propolis Dry Extract ESIT12 : Nutrikinetic and Bioavailability Studies · NA · completed
- NCT05926947 — OXXYNEA® GS: Study for Glycaemia Management · NA · active not recruiting
- NCT05598749 — Poplar-type Propolis Dry Extract ESIT12 : Immunomodulation Efficacy Study · NA · completed
- NCT04914416 — Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04765189 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fytexia
- Last refreshed: 5 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04765189.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing