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NCT04761991: CONCORD
CMR Versus CT in Coronary Artery Disease
trial testing CMR and CTCA with CT-FFR in Coronary Artery Disease in 300 participants. Currently enrolling.
30 November 2025
Quick facts
| Lead sponsor | University of Leicester |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 5 November 2020 |
| Primary completion | 30 November 2025 |
| Estimated completion | 30 November 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- CMR and CTCA with CT-FFR
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
Sponsor
University of Leicester
Who can join
18 and older, any sex, with Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
CONCORD is a prospective observational study evaluating the diagnostic accuracy of cardiovascular magnetic resonance (CMR) and computed tomography with fractional flow reserve (CT-FFR) in patients with suspected coronary artery disease, using invasive fractional flow reserve (FFR) as the reference standard.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Vasoactive breathing manoeuvres as an effective coronary vasodilator in patients with suspected coronary artery disease: a prospective comparative oxygenation-sensitive CMR study.
Shergill S, Hillier E, Velvet A, Budgeon CA, et al · · 2025 · PMID 42163843 · DOI 10.1093/ehjimp/qyaf141 -
Stress T1 mapping for the detection of obstructive coronary artery disease: a prospective diagnostic accuracy study.
Shergill S, Elshibly M, Velvet A, Moafi A, et al · · 2026 · PMID 41619975 · DOI 10.1016/j.jocmr.2026.102701 -
Cardiovascular magnetic resonance versus coronary computed tomography angiography with fractional flow reserve for diagnosing obstructive coronary artery disease in higher risk patients: rationale and design of CONCORD-A prospective, single-center diagnostic accuracy study.
Shergill S, Elshibly M, Parke KS, England R, et al · · 2025 · PMID 40818667 · DOI 10.1016/j.jocmr.2025.101939
Verify or expand the search:
- PubMed search for NCT04761991
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Leicester trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04761991 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Leicester
- Last refreshed: 1 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04761991.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing