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NCT04756778
Indexed Aortic Area in Bicuspid Aortic Valve Aortopathy
trial testing Aortic surgery +/- aortic valve replacement in Thoracic Aortic Aneurysm in 69 participants. Completed in 15 August 2017.
15 May 2017
Quick facts
| Lead sponsor | St. George's Hospital, London |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 69 |
| Start date | 27 January 2017 |
| Primary completion | 15 May 2017 |
| Estimated completion | 15 August 2017 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Aortic surgery +/- aortic valve replacement
Conditions studied
- Thoracic Aortic Aneurysm — all drugs for Thoracic Aortic Aneurysm →
- Bicuspid Cardiac Valve — all drugs for Bicuspid Cardiac Valve →
Sponsor
St. George's Hospital, London
Who can join
18 and older, any sex, with Thoracic Aortic Aneurysm or Bicuspid Cardiac Valve. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to determine the relationship between the cross-sectional aortic area/patient height ratio (indexed aortic area) and absolute aortic diameter in proximal thoracic aortic aneurysms associated with a bicuspid valve. This will shed light on whether aneurysms with smaller diameters than those recommended for surgical intervention by guidelines are still at risk of aortic complications attending an abnormally high indexed aortic area.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Relationship between indexed aortic area and aortic diameter in bicuspid aortic valve aortopathy: A retrospective cohort study.
Acharya M, Valencia O, Edsell M, Tome M, et al · · 2021 · cited 1× · PMID 33996069 · DOI 10.1016/j.amsu.2021.102342
Verify or expand the search:
- PubMed search for NCT04756778
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other St. George's Hospital, London trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04756778 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. George's Hospital, London
- Last refreshed: 16 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04756778.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing