NCT04752410

Selective Trunk Block: A Study to Evaluate Block Dynamics, Effects and Efficacy for Upper Limb Surgery

Completed NA Last updated 28 July 2021

What this trial tests

NA trial testing Selective Brachial Plexus Block in Upper Extremity Problem in 30 participants. Completed in 27 July 2021.

Timeline

19 February 2021

Primary endpoint
27 July 2021

27 July 2021

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	19 February 2021
Primary completion	27 July 2021
Estimated completion	27 July 2021
Sites	1 location across Hong Kong

Drugs / interventions tested

• Selective Brachial Plexus Block

Conditions studied

• Upper Extremity Problem — all drugs for Upper Extremity Problem →

Sponsor

Chinese University of Hong Kong

Who can join

Adults 18 to 80, any sex, with Upper Extremity Problem. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Brachial plexus block (BPB) is frequently used as the sole anesthetic technique for upper extremity surgery. The choice of technique often depends on the site of surgery because the extent of sensory-motor blockade after a BPB varies with the technique used. The investigator is not aware of any single BPB technique described to date that can consistently produce surgical anesthesia of the whole ipsilateral upper extremity. However, occasionally surgery entails that the whole upper extremity, i.e. from the shoulder to the elbow, or even the forearm, wrist or hands. This clinical challenge has been addressed previously using a combination of BPB techniques. The investigator has recently demonstrated that it is feasible to accurately identify majority of the main components of the brachial plexus above the clavicle, including the three trunks, using ultrasound imaging. Since majority of the innervation of the upper extremity, i.e. shoulder, arm, elbow, forearm, wrist and hand, originates from the three trunks of the brachial plexus, the investigator hypothesized that selectively blocking upper, middle, and inferior trunks of the brachial plexus will produce surgical anesthesia of the whole ipsilateral upper extremity. This study is a continuation of a previously approved study with title "Selective Trunk Brachial Plexus Block: A Prospective Non-Randomized Study of Intervention" \[NCT04510259\] after the amendment (study title, protocol and increased sample size) was rejected by local IRB and suggested to submit as a new protocol. The aim of this study is to assess a novel brachial plexus block technique, the selective trunk block (SeTB), and provide preliminary clinical evidence of its effectiveness in producing surgical anesthesia of the whole ipsilateral upper extremity.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Ultrasound-guided selective trunk block: Evaluation of ipsilateral sensorimotor block dynamics, hemidiaphragmatic function and efficacy for upper extremity surgery. A single-centre cohort study.
   Sivakumar RK, Samy W, Pakpirom J, Songthamwat B, et al · · 2022 · cited 8× · PMID 35950709 · DOI 10.1097/eja.0000000000001736