Who is sponsoring NCT04748562?

NCT04748562 is sponsored by Ain Shams University.

What drugs are being tested in NCT04748562?

Interventions in NCT04748562: Progesterone.

What condition does NCT04748562 study?

NCT04748562 studies Twin Pregnancy With Antenatal Problem.

Is NCT04748562 still recruiting?

NCT04748562 is currently completed. Last updated 10 February 2021.

Last reviewed 2021-02-10 · How we verify

NCT04748562

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Vaginal Progesterone 400mg v.s 200mg for Prevention of Preterm Labor in Twin Pregnancies

Completed Phase 4 Last updated 10 February 2021

What this trial tests

Phase 4 trial testing Progesterone in Twin Pregnancy With Antenatal Problem in 100 participants. Completed in 1 December 2020.

Timeline

1 January 2020

Primary endpoint
1 August 2020

1 December 2020

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	100
Start date	1 January 2020
Primary completion	1 August 2020
Estimated completion	1 December 2020
Sites	1 location across Egypt

Drugs / interventions tested

Progesterone (Progesterone plus HCG) — full drug profile →

Conditions studied

Twin Pregnancy With Antenatal Problem — all drugs for Twin Pregnancy With Antenatal Problem →

Sponsor

Ain Shams University

Who can join

Adults 18 to 40, female only, with Twin Pregnancy With Antenatal Problem. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is already known that the risk of preterm labor in twin pregnancy before 37 week is 8-9 fold higher compared to singletons, and progesterone supplementation can decrease the incidence of preterm labor in singleton pregnancy. There were studies that used 200mg vaginal progesterone with no effect on the result So this study aims To examine the effect of prophylactic vaginal progesterone 400mg v.s 200mg for prevention of preterm birth in twin pregnancies

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Progesterone

Trials testing the same drug.

NCT07372495 — Cerclage Plus Progesterone vs Progesterone Alone in Twin Short Cervix · NA · not yet recruiting
NCT06631547 — Effect of Progesterone Administration on Severely Head Injured Patients · Phase 1 · not yet recruiting
NCT07162961 — Nintedanib for Improving Reproductive Outcomes in Adenomyosis · Phase 3 · not yet recruiting
NCT06851754 — Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency · Phase 3 · recruiting
NCT06928844 — Role of Low Dose Injectable Progesterone in Triggering Ovulation · NA · recruiting

Other recruiting trials for Twin Pregnancy With Antenatal Problem

Currently open trials in the same condition.

NCT05894785 — External Cephalic Version (ECV) for Twins With Non-vertex Presenting Twin · NA · recruiting
NCT05144321 — Twin Pregnancy Cohort · active not recruiting
NCT05761769 — Twin Pregnancy: a Challenge for Patients, Families and Health Professionals · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04748562 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 10 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04748562.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing