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NCT04747717
Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer
NA trial testing chemotherapy/surgery in Ovarian Cancer in 30 participants. Status unknown.
1 October 2022
Quick facts
| Lead sponsor | N.N. Petrov National Medical Research Center of Oncology |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 October 2020 |
| Primary completion | 1 October 2022 |
| Estimated completion | 1 October 2025 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- chemotherapy/surgery
Conditions studied
- Ovarian Cancer — all drugs for Ovarian Cancer →
Sponsor
N.N. Petrov National Medical Research Center of Oncology — full company profile →
Who can join
Adults 18 to 75, female only, with Ovarian Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study was designed to assess the safety and efficacy of neoadjuvant therapy with mitomycin C plus cisplatin (MP) in BRCA1-mutated ovarian cancer versus standard regimen (paclitaxel plus carboplatin (TP)).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of outcomes of neoadjuvant chemotherapy in <i>BRCA1</i>- versus <i>BRCA2</i>-associated breast and ovarian cancers.
Sokolenko A, Gorodnova T, Enaldieva D, Shestakova A, et al · · 2025 · cited 2× · PMID 40547808 · DOI 10.37349/etat.2025.1002325
Verify or expand the search:
- PubMed search for NCT04747717
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ovarian Cancer
Currently open trials in the same condition.
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- NCT07318558 — A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021) · Phase 3 · recruiting
- NCT07491081 — EARLY Study: Evaluating the Specificity and Feasibility of the EARLY Biomarker Panel for Ovarian Cancer Detection · NA · recruiting
- NCT07410676 — EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors · Phase 1, PHASE2 · recruiting
Other N.N. Petrov National Medical Research Center of Oncology trials
Trials by the same sponsor.
- NCT06418789 — High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors · Phase 2 · recruiting
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- NCT06229340 — Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations · Phase 2 · recruiting
- NCT06043947 — Survival Monitoring in Russian Cancer Registries · active not recruiting
- NCT05468827 — ICG Fluorescence Guided Lymph Node Mapping for Determination of Bowel Resection Margins in Colon Cancer · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04747717 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by N.N. Petrov National Medical Research Center of Oncology
- Last refreshed: 11 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04747717.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing