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NCT04744818: VINO
Effects of Iron Supplementation on Pediatric Vaccine Response
NA trial testing Iron syrup in Iron-deficiency in 288 participants. Completed in 16 October 2023.
3 April 2023
Quick facts
| Lead sponsor | Jessica Rigutto |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | other |
| Enrollment | 288 |
| Start date | 7 February 2021 |
| Primary completion | 3 April 2023 |
| Estimated completion | 16 October 2023 |
| Sites | 2 locations across Kenya, Switzerland |
Drugs / interventions tested
- Iron syrup
- Multivitamin syrup
Conditions studied
- Iron-deficiency — all drugs for Iron-deficiency →
- Iron Deficiency Anemia — all drugs for Iron Deficiency Anemia →
- Vaccination — all drugs for Vaccination →
- Pediatric ALL — all drugs for Pediatric ALL →
Sponsor
Jessica Rigutto
Who can join
Adults 39 Days to 45 Days, any sex, with Iron-deficiency or Iron Deficiency Anemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
ID/IDA affects many young children in Africa. Vaccines provide tremendous benefits in LMIC; however, they currently fail to reach their full potential. We need to better understand the causes of vaccine failure, in order to develop new strategies to improve vaccine immunogenicity. This study will contribute to children's health by: (1) providing updated guidelines to better define the prevalence of ID/IDA in early infancy, and its safe and effective control using iron; and (2) providing a new approach to improve response to pediatric vaccines in LMIC, by ensuring adequate iron status at time of vaccination.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04744818
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Iron syrup
Trials testing the same drug.
- NCT06816524 — The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency · NA · not yet recruiting
Other recruiting trials for Iron-deficiency
Currently open trials in the same condition.
- NCT05407987 — Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery) · Phase 3 · recruiting
- NCT06270498 — Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure · Phase 4 · recruiting
- NCT05913414 — Iron Isomaltide for Iron-deficiency Anemia Patients With Locally Advanced Nasopharyngeal Carcinoma · Phase 2 · recruiting
- NCT05340465 — Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants · Phase 2 · recruiting
- NCT07083492 — Non-invasive Detection of Iron Deficiency in Obstetrics · recruiting
Other Jessica Rigutto trials
Trials by the same sponsor.
- NCT06657677 — Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04744818 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jessica Rigutto
- Last refreshed: 24 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04744818.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing