Who is sponsoring NCT04743960?

NCT04743960 is sponsored by Massachusetts General Hospital.

What drugs are being tested in NCT04743960?

Interventions in NCT04743960: Time-of-day of parenteral nutrition provision.

What condition does NCT04743960 study?

NCT04743960 studies Feeding Patterns, Sleep, Glucose Intolerance, Short Bowel Syndrome.

Is NCT04743960 still recruiting?

NCT04743960 is currently completed. Last updated 25 September 2025.

Last reviewed 2025-09-25 · How we verify

NCT04743960

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition

Completed NA Last updated 25 September 2025

What this trial tests

NA trial testing Time-of-day of parenteral nutrition provision in Feeding Patterns in 20 participants. Completed in 24 October 2022.

Timeline

5 October 2021

Primary endpoint
24 October 2022

24 October 2022

Quick facts

Lead sponsor	Massachusetts General Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	20
Start date	5 October 2021
Primary completion	24 October 2022
Estimated completion	24 October 2022
Sites	1 location across United States

Drugs / interventions tested

Time-of-day of parenteral nutrition provision

Conditions studied

Feeding Patterns — all drugs for Feeding Patterns →
Sleep — all drugs for Sleep →
Glucose Intolerance — all drugs for Glucose Intolerance →
Short Bowel Syndrome — all drugs for Short Bowel Syndrome →

Sponsor

Massachusetts General Hospital

Who can join

Adults 18 to 79, any sex, with Feeding Patterns or Sleep. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine whether advancing the timing of home parenteral nutrition from overnight to daytime regimens leads to improved glucose profiles and sleep quality, and other changes in plasma metabolic signatures.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Glycemic and sleep effects of daytime compared with those of overnight infusions of home parenteral nutrition in adults with short bowel syndrome: A quasi-experimental pilot trial.
Dashti HS, Leong A, Mogensen KM, Annambhotla M, et al · · 2024 · cited 5× · PMID 38043867 · DOI 10.1016/j.ajcnut.2023.11.016
Plasma metabolomics changes comparing daytime to overnight infusions of home parenteral nutrition in adult patients with short bowel syndrome: Secondary analysis of a clinical trial.
Dashti HS, Sevilla-Gonzalez M, Mogensen KM, Winkler MF, et al · · 2024 · cited 1× · PMID 38901946 · DOI 10.1016/j.clnesp.2024.04.025

Verify or expand the search:

Other recruiting trials for Feeding Patterns

Currently open trials in the same condition.

NCT06601439 — Utilization of Maternal Healthcare Services and Infant Feeding Practices · active not recruiting
NCT04737200 — The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU · NA · recruiting

Other Massachusetts General Hospital trials

Trials by the same sponsor.

NCT03585946 — Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis · withdrawn
NCT07214831 — A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerg · NA · not yet recruiting
NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04743960 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
Last refreshed: 25 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04743960.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing