Last reviewed · How we verify
NCT04742478: ROVUS
ROVUS Asia Registry (Evaluate Safety and Effectiveness of Rotational Atherectomy and Intravascular Ultrasound for Heavily Calcified Coronary Lesion)
trial testing Rotational Atherectomy in Coronary Artery Calcification in 1,000 participants. Currently enrolling.
29 February 2024
Quick facts
| Lead sponsor | National Heart Centre Singapore |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 10 March 2021 |
| Primary completion | 29 February 2024 |
| Estimated completion | 31 December 2026 |
| Sites | 2 locations across Singapore, Japan |
Drugs / interventions tested
- Rotational Atherectomy
Conditions studied
- Coronary Artery Calcification — all drugs for Coronary Artery Calcification →
Sponsor
National Heart Centre Singapore — full company profile →
Who can join
21 and older, any sex, with Coronary Artery Calcification. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Rotablation with or without other calcium debulking therapies is a safe adjunctive procedure for patients with severe coronary calcification requiring Percutaneous Coronary Intervention (PCI).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04742478
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Rotational Atherectomy
Trials testing the same drug.
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- NCT03806621 — Rota China Registry · completed
Other recruiting trials for Coronary Artery Calcification
Currently open trials in the same condition.
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- NCT07400406 — A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries · recruiting
- NCT06181240 — Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE) · NA · active not recruiting
- NCT05845424 — High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium · Phase 4 · recruiting
- NCT05346068 — The Value of IVL Compared To OPN Non-Compliant Balloons for Treatment of RefractorY Coronary Lesions (VICTORY) Trial · NA · recruiting
Other National Heart Centre Singapore trials
Trials by the same sponsor.
- NCT06645691 — Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body · Phase 2 · recruiting
- NCT05912218 — REducing Diabetic MacrovascUlar Complications DuE to Peripheral Arterial Disease- REDUCE-PAD · Phase 2 · active not recruiting
- NCT05946174 — Tackling Disruptions to Frailty Interventions: Developing Personalized Interventions Targeted for Older Persons With Car · NA · recruiting
- NCT05775484 — Exercise to Slow Cardiovascular Ageing Progression · recruiting
- NCT07376993 — Pulse Signal Acquisition in Patients With Heart Failure · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04742478 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Heart Centre Singapore
- Last refreshed: 23 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04742478.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing