NCT04742140 is a Phase 4 clinical trial of Magnesium sulfate in Trigger Point Pain, Myofascial, sponsored by Fayoum University.

Who is sponsoring NCT04742140?

NCT04742140 is sponsored by Fayoum University.

What drugs are being tested in NCT04742140?

Interventions in NCT04742140: Magnesium sulfate, Saline.

What condition does NCT04742140 study?

NCT04742140 studies Trigger Point Pain, Myofascial.

Is NCT04742140 still recruiting?

NCT04742140 is currently completed. Last updated 7 December 2021.

Last reviewed 2021-12-07 · How we verify

NCT04742140

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points

Completed Phase 4 Last updated 7 December 2021

What this trial tests

Phase 4 trial testing Magnesium sulfate in Trigger Point Pain, Myofascial in 180 participants. Completed in 1 September 2021.

Timeline

20 February 2021

Primary endpoint
20 August 2021

1 September 2021

Quick facts

Lead sponsor	Fayoum University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	180
Start date	20 February 2021
Primary completion	20 August 2021
Estimated completion	1 September 2021
Sites	1 location across Egypt

Drugs / interventions tested

Magnesium sulfate — full drug profile →
Saline

Conditions studied

Trigger Point Pain, Myofascial — all drugs for Trigger Point Pain, Myofascial →

Sponsor

Fayoum University

Who can join

Adults 18 to 60, any sex, with Trigger Point Pain, Myofascial. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, single- center, randomized (1:1) clinical trial comparing the effectiveness of magnesium sulphate injections in treatment of myofascial trigger points in the masseter muscle versus the saline injection.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Clinical efficacy of magnesium sulfate injection in the treatment of masseter muscle trigger points: a randomized clinical study.
Refahee SM, Mahrous AI, Shabaan AA. · · 2022 · cited 6× · PMID 36123724 · DOI 10.1186/s12903-022-02452-3

Verify or expand the search:

Other trials of Magnesium sulfate

Trials testing the same drug.

NCT07524972 — Antenatal Magnesium Sulphate in High-Risk Preterm Patients · Phase 3 · recruiting
NCT07438366 — Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post- · NA · not yet recruiting
NCT07213037 — Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sin · Phase 3 · not yet recruiting
NCT06979141 — Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia · Phase 3 · recruiting
NCT07131033 — Esketamine Combined With Magnesium Sulfate for Postoperative Fatigue Syndrome in Patients Undergoing Laparoscopic Cholec · Phase 1, PHASE2 · active not recruiting

Other recruiting trials for Trigger Point Pain, Myofascial

Currently open trials in the same condition.

NCT07138807 — Effect of MET vs Neck Calliet Exercises on Neck Pain and Disability in Nurses · NA · recruiting
NCT06986707 — Strain Counterstrain Technique and Graston Technqiue on Quadratus Lumborum Trigger Points · NA · recruiting
NCT06986317 — Effectiveness of Positional Release Techniques and Graston Technique In Trigger Point · NA · recruiting
NCT06664359 — Safe Zone in Trigger Point Injection · recruiting
NCT06316583 — Clinical Study on Dry Needling for Primary Dysmenorrhea and Its Preliminary Correlation With Acupoints · NA · recruiting

Other Fayoum University trials

Trials by the same sponsor.

NCT07536620 — Metformin and Alveolar Cleft · Phase 2 · not yet recruiting
NCT07444970 — Comparative Evaluation of Xenograft Alone and Sticky Bone in Sinus Lift With Concurrent Implant Placement · NA · not yet recruiting
NCT07394179 — Transforming Channel Osteotomy Into Tunnel Osteotomy in Zygomatic Implant Preparation · NA · not yet recruiting
NCT07277348 — Analysis of The Outcomes of Therapeutic Photorefractive Keratectomy Combined With Prophylactic Accelerated Cross-Linking · NA · not yet recruiting
NCT07330726 — Lidocaine Patch and Lower Third Molar · Phase 3 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04742140 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fayoum University
Last refreshed: 7 December 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04742140.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing