Who is sponsoring NCT04742114?

NCT04742114 is sponsored by Qilu Hospital of Shandong University.

What drugs are being tested in NCT04742114?

Interventions in NCT04742114: use the face mask with Expiratory Positive Airway Pressure(EPAP)., use the face mask without Expiratory Positive Airway Pressure(EPAP)..

What condition does NCT04742114 study?

NCT04742114 studies Emphysema, Bullous Disease Lung.

Is NCT04742114 still recruiting?

NCT04742114 is currently status unknown. Last updated 29 March 2022.

Last reviewed 2022-03-29 · How we verify

NCT04742114

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of EPAP Device on Emphysema and Lung Bullae

Status unknown NA Last updated 29 March 2022

What this trial tests

NA trial testing use the face mask with Expiratory Positive Airway Pressure(EPAP). in Emphysema in 200 participants. Status unknown.

Timeline

31 July 2021

Primary endpoint
10 November 2022

20 November 2022

Quick facts

Lead sponsor	Qilu Hospital of Shandong University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	200
Start date	31 July 2021
Primary completion	10 November 2022
Estimated completion	20 November 2022
Sites	1 location across China

Drugs / interventions tested

use the face mask with Expiratory Positive Airway Pressure(EPAP).
use the face mask without Expiratory Positive Airway Pressure(EPAP).

Conditions studied

Emphysema — all drugs for Emphysema →
Bullous Disease Lung — all drugs for Bullous Disease Lung →

Sponsor

Qilu Hospital of Shandong University

Who can join

Under 75, any sex, with Emphysema or Bullous Disease Lung. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the safety and the effects and of the application of Expiratory Positive Airway Pressure (EPAP) device on Dynamic Hyperinflation and dyspnea in patients with Emphysema and pulmonary bullae.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy and safety of long-term use of a positive expiratory pressure device in chronic obstructive pulmonary disease patients, a randomized controlled trial.
Xu Z, Han Z, Ma D. · · 2023 · cited 5× · PMID 36647057 · DOI 10.1186/s12890-023-02319-5

Verify or expand the search:

Other recruiting trials for Emphysema

Currently open trials in the same condition.

NCT07059637 — Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD · NA · recruiting
NCT06891755 — Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3 · NA · recruiting
NCT06025500 — Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment · recruiting
NCT06533371 — Clinical-ultrasonographic Assessment of Pulmonary Emphysema · NA · recruiting
NCT06528418 — Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath · recruiting

Other Qilu Hospital of Shandong University trials

Trials by the same sponsor.

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NCT07509879 — Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder · not yet recruiting
NCT07537374 — A Case-Control Observational Study of Peripheral Blood-Derived iPSC Models to Investigate Oligodendrocyte Lineage Develo · not yet recruiting
NCT07505940 — Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04742114 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Qilu Hospital of Shandong University
Last refreshed: 29 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04742114.

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