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NCT04741178: Paesi-COV-19

PAtterns and Extension in COVID-19 Related Interstitial Pneumonia: CT Analysis

Status unknown Last updated 10 February 2021
What this trial tests

trial in Covid19 in 600 participants. Status unknown.

Timeline
20 March 2020
Primary endpoint
2 January 2021
31 December 2021

Quick facts

Lead sponsorMorgagni Pierantoni Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment600
Start date20 March 2020
Primary completion2 January 2021
Estimated completion31 December 2021
Sites1 location across Italy

Conditions studied

Sponsor

Morgagni Pierantoni Hospital

Who can join

Adults 18 to 90, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The hallmark of the L phenotype is the vasoplegia, as confirmed by the rapid change in density and distribution of CT findings from the supine to the prone position. The benefit of a prone position in awake, nonintubated, spontaneously breathing Covid-19 patients has been emerging as potential tool to improve oxygenation and to prevent the access to ICU. No evidence of radiological modifications related to Aim of our study is to evaluate CT changes in terms of extension, distribution and prevalence of findings, in the supine compared with the prone position.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Supine vs prone position in mild to moderate COVID-19 pneumonia: The impact of proning on computed tomography findings.
    Piciucchi S, Garo ML, Tomassetti S, Ravaglia C, et al · · 2022 · PMID 35738975 · DOI 10.1016/j.ejim.2022.06.012

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