NCT04740528 is a clinical trial of fto gene testing in Obesity Adult Onset, sponsored by Universitas Diponegoro.

Who is sponsoring NCT04740528?

NCT04740528 is sponsored by Universitas Diponegoro.

What drugs are being tested in NCT04740528?

Interventions in NCT04740528: fto gene testing.

What condition does NCT04740528 study?

NCT04740528 studies Obesity Adult Onset.

Is NCT04740528 still recruiting?

NCT04740528 is currently completed. Last updated 2 March 2021.

Last reviewed 2021-03-02 · How we verify

NCT04740528

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Preference of Protein Intake and FTO rs1558902 Gene Polymorphism Among Women Obese

Completed Last updated 2 March 2021

What this trial tests

trial testing fto gene testing in Obesity Adult Onset in 130 participants. Completed in 30 November 2020.

Timeline

1 August 2020

Primary endpoint
1 October 2020

30 November 2020

Quick facts

Lead sponsor	Universitas Diponegoro
Status	Completed
Study type	OBSERVATIONAL
Enrollment	130
Start date	1 August 2020
Primary completion	1 October 2020
Estimated completion	30 November 2020
Sites	1 location across Indonesia

Drugs / interventions tested

fto gene testing

Conditions studied

Obesity Adult Onset — all drugs for Obesity Adult Onset →

Sponsor

Universitas Diponegoro — full company profile →

Who can join

Adults 35 to 45, female only, with Obesity Adult Onset. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The concept personalized gene-based nutrition combines genetic information with specific dietary intake that is crucial in managing obesity. Obesity experienced by adult women is generally caused by inapproriate diet and sedentary lifestyle. Variations in the fat mass and obesity-related gene (FTO) has been linked with susceptibility to obesity, but diet seems to change the relationship. A single nucleotide polymorphism (SNP) in the fat mass and obesity-associated gene (FTO) is a potent predictor of human obesity. Higher protein diets were more appropriate than standard protein diets, and frequently recommended as a weight loss plan as it prevents the loss of lean tissue mass. Nevertheless, high intakes of proteins may adversely affect metabolic functions. Multi studies have explored associated FTO polymorphisms with obesity in different populations. However, the contribution of the FTO common variants to obesity is controversial in Asian people, some studies showed rs1558902 was statistically associated with BMI, but other results reported FTO gene is not statistically associated with obesity. Given the diversity of Asian populations, the investigators generated a hypothesis whether relations between preference protein intake and FTO rs1558902 gene polymorphism exist in selected Indonesian obesity women

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

RNA modifications in cellular metabolism: implications for metabolism-targeted therapy and immunotherapy.
Liu WW, Zheng SQ, Li T, Fei YF, et al · · 2024 · cited 112× · PMID 38531882 · DOI 10.1038/s41392-024-01777-5

Verify or expand the search:

Other recruiting trials for Obesity Adult Onset

Currently open trials in the same condition.

NCT05887271 — A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejec · Phase 2, PHASE3 · recruiting

Other Universitas Diponegoro trials

Trials by the same sponsor.

NCT07011199 — Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia · Phase 1 · not yet recruiting
NCT07149961 — Curcumin-Piperine Supplementation in STEMI - SPICE STEMI Trial · NA · completed
NCT07058857 — The Effect of Low-Level Tragus Stimulation on Echocardiographic Parameters in Patients With ST-Segment Elevation Myocard · NA · recruiting
NCT06475105 — Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes · Phase 4 · recruiting
NCT06448624 — Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation · Phase 4 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04740528 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitas Diponegoro
Last refreshed: 2 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04740528.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing