NCT04738773 is a Phase 2 clinical trial of Naltrexone in Eye Tracking, sponsored by University of Sao Paulo.

Who is sponsoring NCT04738773?

NCT04738773 is sponsored by University of Sao Paulo.

What drugs are being tested in NCT04738773?

Interventions in NCT04738773: Naltrexone, Placebo.

What condition does NCT04738773 study?

NCT04738773 studies Eye Tracking, Gambling Disorder, Naltrexone.

Is NCT04738773 still recruiting?

NCT04738773 is currently status unknown. Last updated 3 February 2021.

Last reviewed 2021-02-03 · How we verify

NCT04738773

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Double Blind 12-week Controlled Experiment With Two Groups of Pathological Gamblers, One Taking Active Drug (Naltrexone) and the Other Receiving Placebo.Patters Patterns of Visual Tracking Will be Acessed on Both Groups Prior and During Tratment in Order to Predict Treatment Response

Status unknown Phase 2 Last updated 3 February 2021

What this trial tests

Phase 2 trial testing Naltrexone in Eye Tracking in 40 participants. Status unknown.

Timeline

1 June 2021

Primary endpoint
1 July 2022

1 December 2023

Quick facts

Lead sponsor	University of Sao Paulo
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	40
Start date	1 June 2021
Primary completion	1 July 2022
Estimated completion	1 December 2023

Drugs / interventions tested

Naltrexone — full drug profile →
Placebo

Conditions studied

Eye Tracking — all drugs for Eye Tracking →
Gambling Disorder — all drugs for Gambling Disorder →
Naltrexone — all drugs for Naltrexone →

Sponsor

University of Sao Paulo

Who can join

Adults 21 to 60, any sex, with Eye Tracking or Gambling Disorder. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Gambling Follow up scale (GFS)
Time frame: Day 0 and day 84

Sponsor's own description

The primary objective of this study is to determine whether favorable response to naltrexone orally taken in treatment of GD can be predicted by patterns of visual scanning, assessed by eye-tracking technology before, at the start and throughout gambling treatment with naltrexone.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pharmacological interventions for the treatment of disordered and problem gambling.
Dowling N, Merkouris S, Lubman D, Thomas S, et al · · 2022 · cited 10× · PMID 36130734 · DOI 10.1002/14651858.cd008936.pub2

Verify or expand the search:

Other trials of Naltrexone

Trials testing the same drug.

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Other University of Sao Paulo trials

Trials by the same sponsor.

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NCT07445178 — Piecemeal Resection and Advanced Histology Independently Predict Local Recurrence After Colorectal Snare-based Endoscopi · completed
NCT07170007 — Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal Trauma · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04738773 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
Last refreshed: 3 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04738773.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing