Who is sponsoring NCT04736498?

NCT04736498 is sponsored by Tribhuvan University, Nepal.

What drugs are being tested in NCT04736498?

Interventions in NCT04736498: Inferior venacava Ultrasonography (IVC USG) guided fluid management.

What condition does NCT04736498 study?

NCT04736498 studies Hypotension, Fluid Overload.

Is NCT04736498 still recruiting?

NCT04736498 is currently completed. Last updated 5 February 2021.

Last reviewed 2021-02-05 · How we verify

NCT04736498

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Inferior Venacava Ultrasound to Guide Fluid Management for Prevention of Hypotension After Spinal Anesthesia.

Completed NA Last updated 5 February 2021

What this trial tests

NA trial testing Inferior venacava Ultrasonography (IVC USG) guided fluid management in Hypotension in 92 participants. Completed in 20 January 2020.

Timeline

12 December 2018

Primary endpoint
10 September 2019

20 January 2020

Quick facts

Lead sponsor	Tribhuvan University, Nepal
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	92
Start date	12 December 2018
Primary completion	10 September 2019
Estimated completion	20 January 2020
Sites	1 location across Nepal

Drugs / interventions tested

Inferior venacava Ultrasonography (IVC USG) guided fluid management

Conditions studied

Hypotension — all drugs for Hypotension →
Fluid Overload — all drugs for Fluid Overload →

Sponsor

Tribhuvan University, Nepal

Who can join

Adults 16 to 65, any sex, with Hypotension or Fluid Overload. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hypotension is common during spinal anesthesia and contributes to underperfusion and ischemia. Severe episodes of intraoperative hypotension is an independent risk factor for myocardial infarction, stroke, heart failure, acute kidney injury, prolonged hospital stay and increased one year mortality rates. Empiric fluid preloading can be done to decrease the incidence of hypotension but carries risk of fluid overload especially in elderly and cardiac patients. Inferior venacava ultrasonography (IVC USG) has been used in spontaneously breathing critically ill patients for volume responsiveness but there is limited data regarding its use for volume optimization in perioperative setting. The aim of this study is to evaluate the use of inferior venacava ultrasound to guide fluid management for prevention of hypotension after spinal anesthesia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Inferior vena cava ultrasound to guide fluid management for prevention of hypotension after spinal anesthesia in a tertiary level teaching hospital.
Dahal S, Pradhan B, Bhattarai AS, Paudyal SP, et al · · 2026 · PMID 41497009 · DOI 10.1097/ms9.0000000000004449

Verify or expand the search:

Other recruiting trials for Hypotension

Currently open trials in the same condition.

NCT07499947 — Predicting Spinal Hypotension in Cesarean Section · recruiting
NCT07494955 — "Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section" · NA · recruiting
NCT07481851 — Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients · recruiting
NCT06994494 — Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS · recruiting
NCT06953193 — Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia · NA · recruiting

Other Tribhuvan University, Nepal trials

Trials by the same sponsor.

NCT06214585 — Effect of Intermittent Heat and Cold Therapy on Comfort During Labor · NA · completed
NCT05725226 — Comparison Between 6Fr Vs 4Fr Double J Stent · NA · completed
NCT05955352 — The Effect of Using Perineal Warm Compress Techniques During the Second Stage of Labor on Perineal Outcomes · NA · completed
NCT06391021 — Comparison Between Combined Scoring of Bethesda Cytology and TIRADS Ultrasound With Histopathology in Thyroid Nodule · completed
NCT06152055 — Clinicopathological Profile of Head and Neck Cancers in Army Hospital of Nepal · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04736498 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tribhuvan University, Nepal
Last refreshed: 5 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04736498.

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