Last reviewed · How we verify
NCT04731415
Physiologic Change of Posterior Ocular Segment During Pregnancy
NA trial testing Optical coherence tomography and optical coherence tomography angiography (Optovue®) in Retinal Vascular in 69 participants. Not yet recruiting.
30 December 2025
Quick facts
| Lead sponsor | Khon Kaen University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 69 |
| Start date | 1 July 2021 |
| Primary completion | 30 December 2025 |
| Estimated completion | 30 June 2026 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Optical coherence tomography and optical coherence tomography angiography (Optovue®)
Conditions studied
- Retinal Vascular — all drugs for Retinal Vascular →
Sponsor
Khon Kaen University
Who can join
18 and older, female only, with Retinal Vascular. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Women's physiology changes markedly during normal pregnancy. The most distinct alterations occur in the hormonal and cardiovascular systems. There is a dramatic increase in both estrogen and progesterone. Blood volume starts to increase in the first gestational period and reaches a peak in the third trimester. The physiologic ocular changes during pregnancy are mainly the result of hormonal and blood volume increase, and then are usually marked in the third trimester.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04731415
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Khon Kaen University trials
Trials by the same sponsor.
- NCT07494396 — An AI-Based Erythema Measurement System for Psoriasis Lesions · not yet recruiting
- NCT07054775 — Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section · Phase 4 · recruiting
- NCT06994520 — Efficacy of Topical Cannabidiol for Eczema · Phase 2 · active not recruiting
- NCT06958029 — Postoperative Atrial Fibrillation in Cardiac Surgery · recruiting
- NCT06289257 — Analysis of Vitamin D and VDR Expression in Endometriosis: A Case-Control Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04731415 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khon Kaen University
- Last refreshed: 30 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04731415.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing