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NCT04730284
Evaluation of a Synbiotic Formula in Patient With COVID-19
NA trial testing Health supplements in Coronavirus in 20 participants. Status unknown.
30 September 2021
Quick facts
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 20 |
| Start date | 25 August 2020 |
| Primary completion | 30 September 2021 |
| Estimated completion | 31 March 2022 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- Health supplements
Conditions studied
- Coronavirus — all drugs for Coronavirus →
Sponsor
Chinese University of Hong Kong
Who can join
18 and older, any sex, with Coronavirus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A series of microbiota were correlated inversely with the disease severity and virus load. Gut microbiota could play a role in modulating host immune response and potentially influence disease severity and outcomes.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Evidences and perspectives of the use of probiotics, prebiotics, synbiotics, and postbiotics as adjuvants for prevention and treatment of COVID-19: A bibliometric analysis and systematic review.
Xavier-Santos D, Padilha M, Fabiano GA, Vinderola G, et al · · 2022 · cited 76× · PMID 35002079 · DOI 10.1016/j.tifs.2021.12.033 -
Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients.
Su Q, Liu Q, Zhang L, Xu Z, et al · · 2022 · cited 18× · PMID 36201636 · DOI 10.1080/19490976.2022.2128603 -
Targeting the Gut Microbiota in Coronavirus Disease 2019: Hype or Hope?
Lau HC, Ng SC, Yu J. · · 2022 · cited 16× · PMID 34508775 · DOI 10.1053/j.gastro.2021.09.009 -
Probiotics: A gut response to the COVID-19 pandemic but what does the evidence show?
Brahma S, Naik A, Lordan R. · · 2022 · cited 11× · PMID 36184201 · DOI 10.1016/j.clnesp.2022.08.023 -
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections.
Kaushal A. · · 2024 · cited 2× · PMID 39294611 · DOI 10.1186/s12967-024-05587-9 -
Corrigendum to 'Evidences and perspectives of the use of probiotics, prebiotics, synbiotics, and postbiotics as adjuvants for prevention and treatment of COVID-19: A bibliometric analysis and integrative review' [Trends in Food Science & Technology 120 (2022) 174-192].
Xavier-Santos D, Padilha M, Fabiano GA, Vinderola G, et al · · 2022 · cited 2× · PMID 35125655 · DOI 10.1016/j.tifs.2022.01.028
Verify or expand the search:
- PubMed search for NCT04730284
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04730284 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
- Last refreshed: 29 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04730284.
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