Last reviewed · How we verify

NCT04730284

Evaluation of a Synbiotic Formula in Patient With COVID-19

Status unknown NA Last updated 29 January 2021
What this trial tests

NA trial testing Health supplements in Coronavirus in 20 participants. Status unknown.

Timeline
25 August 2020
Primary endpoint
30 September 2021
31 March 2022

Quick facts

Lead sponsorChinese University of Hong Kong
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeother
Enrollment20
Start date25 August 2020
Primary completion30 September 2021
Estimated completion31 March 2022
Sites1 location across Hong Kong

Drugs / interventions tested

Conditions studied

Sponsor

Chinese University of Hong Kong

Who can join

18 and older, any sex, with Coronavirus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A series of microbiota were correlated inversely with the disease severity and virus load. Gut microbiota could play a role in modulating host immune response and potentially influence disease severity and outcomes.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Evidences and perspectives of the use of probiotics, prebiotics, synbiotics, and postbiotics as adjuvants for prevention and treatment of COVID-19: A bibliometric analysis and systematic review.
    Xavier-Santos D, Padilha M, Fabiano GA, Vinderola G, et al · · 2022 · cited 76× · PMID 35002079 · DOI 10.1016/j.tifs.2021.12.033
  2. Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients.
    Su Q, Liu Q, Zhang L, Xu Z, et al · · 2022 · cited 18× · PMID 36201636 · DOI 10.1080/19490976.2022.2128603
  3. Targeting the Gut Microbiota in Coronavirus Disease 2019: Hype or Hope?
    Lau HC, Ng SC, Yu J. · · 2022 · cited 16× · PMID 34508775 · DOI 10.1053/j.gastro.2021.09.009
  4. Probiotics: A gut response to the COVID-19 pandemic but what does the evidence show?
    Brahma S, Naik A, Lordan R. · · 2022 · cited 11× · PMID 36184201 · DOI 10.1016/j.clnesp.2022.08.023
  5. Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections.
    Kaushal A. · · 2024 · cited 2× · PMID 39294611 · DOI 10.1186/s12967-024-05587-9
  6. Corrigendum to 'Evidences and perspectives of the use of probiotics, prebiotics, synbiotics, and postbiotics as adjuvants for prevention and treatment of COVID-19: A bibliometric analysis and integrative review' [Trends in Food Science & Technology 120 (2022) 174-192].
    Xavier-Santos D, Padilha M, Fabiano GA, Vinderola G, et al · · 2022 · cited 2× · PMID 35125655 · DOI 10.1016/j.tifs.2022.01.028

Verify or expand the search:

Other trials of Health supplements

Trials testing the same drug.

Other recruiting trials for Coronavirus

Currently open trials in the same condition.

Other Chinese University of Hong Kong trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04730284.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing