NCT04724902

The Effect of Elastic Bandage Compression on Pain and Function in Individuals With Knee Osteoarthritis

Completed NA Last updated 6 May 2023

What this trial tests

NA trial testing Elastic bandage compression in Knee Osteoarthritis in 90 participants. Completed in 31 March 2023.

Timeline

1 October 2021

Primary endpoint
30 November 2022

31 March 2023

Quick facts

Lead sponsor	Universidade Federal de Sao Carlos
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	90
Start date	1 October 2021
Primary completion	30 November 2022
Estimated completion	31 March 2023
Sites	1 location across Brazil

Drugs / interventions tested

• Elastic bandage compression

Conditions studied

• Knee Osteoarthritis — all drugs for Knee Osteoarthritis →

Sponsor

Universidade Federal de Sao Carlos

Who can join

Adults 40 to 75, any sex, with Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction and Purpose: Compression is a tactile stimulus that can reduce the perception of pain by stimulating tactile skin receptors and the speed of nerve conduction. It is highly associated with cryotherapy and other non-pharmacological physical agents without musculoskeletal pain control. However, there is still a lack of evidence on its possible effects on the modulation of this type of pain. This study will evaluate the effect of compression by elastic bandages, on pain and on the function of belonging with knee osteoarthritis (KO). Methodology: A randomized, blinded controlled clinical trial will be conducted. Individuals with KO (n = 90; both sexes; between 40 and 75 years old), will be allocated into three groups (n = 30 / group): Compression (submitted to compression by elastic bandage on the affected knee, 20 min, in 4 days consecutive); Sham (submitted to the same protocol with elastic bandage, but without compression); and Control (waiting list, without intervention). All will be taken one day before the start and one day after the last intervention. They will also be adopted in the 12th and 24th weeks after the intervention. The main outcome will be the pain intensity (Visual Analogue Scale). The Western Ontario \& McMaster Universities Osteoarthritis (WOMAC) physical function questionnaire, physical function tests (step test, sit and stand test in 30s, 40m accelerated walk test), and the perception scale global change (GRC). Data analysis: SPSS 24.0 software will be used for descriptive analysis and performance of Kolmogorov-Smirnov tests, two-way ANOVA and multiple comparison tests. A 95% confidence level and a 5% significance level will be adopted.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effect of compression by elastic bandages on pain and function in individuals with knee osteoarthritis: protocol of a randomised controlled clinical trial.
   Ferrari AV, Perea JPM, Dantas LO, Silva HJA, et al · · 2022 · cited 1× · PMID 36385041 · DOI 10.1136/bmjopen-2022-066542