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NCT04723355

A Comparative Study of an Innovative 3-lead Wireless Water Resistant Holter System and a Conventional Holter System

Completed NA Results posted Last updated 24 October 2024
What this trial tests

NA trial testing An innovative 3-lead wireless water resistant Holter device in Cardiac Arrhythmia in 231 participants. Completed in 16 November 2021.

Timeline
26 January 2021
Primary endpoint
16 November 2021
16 November 2021

Quick facts

Lead sponsorHospital Israelita Albert Einstein
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment231
Start date26 January 2021
Primary completion16 November 2021
Estimated completion16 November 2021
Sites1 location across Brazil

Drugs / interventions tested

Conditions studied

Sponsor

Hospital Israelita Albert Einstein

Who can join

18 and older, any sex, with Cardiac Arrhythmia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Detection of Cardiac Arrhythmias Primary · 24 hours

Number of patients with cardiac arrhythmias detected in both Holter monitors, including a) atrial fibrillation or atrial flutter; b) supraventricular tachycardia (any tachycardia with ≥ 3 beats arising outside the sinus node and above the His-Purkinje bifurcation, including atrial tachycardia, atrioventricular nodal reentry tachycardia, junctional tachycardia and accessory pathway reentry tachycardia, except atrial fibrillation and atrial flutter); c) ventricular tachycardia (any tachycardia with ≥ 3 beats arising from the ventricles, except polymorphic ventricular tachycardia or ventricular f

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device107
Conventional Holter System
GroupValue95% CI
Holter Device104
Detection of Atrial Fibrillation or Atrial Flutter Secondary · 24 hours

Number of patients with atrial fibrillation or atrial flutter detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device23
Conventional Holter System
GroupValue95% CI
Holter Device22
Detection of Supraventricular Tachycardia Secondary · 24 hours

Number of patients with supraventricular tachycardia (any tachycardia with ≥ 3 beats arising outside the sinus node and above the His-Purkinje bifurcation, including atrial tachycardia, atrioventricular nodal reentry tachycardia, junctional tachycardia and accessory pathway reentry tachycardia, except atrial fibrillation and atrial flutter) detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device71
Conventional Holter System
GroupValue95% CI
Holter Device71
Detection of Ventricular Tachycardia Secondary · 24 hours

Number of patients with ventricular tachycardia (any tachycardia with ≥ 3 beats arising from the ventricles, except polymorphic ventricular tachycardia or ventricular fibrillation) detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device26
Conventional Holter System
GroupValue95% CI
Holter Device23
Detection of Polymorphic Ventricular Tachycardia or Ventricular Fibrillation Secondary · 24 hours

Number of patients with polymorphic ventricular tachycardia or ventricular fibrillation detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device14
Conventional Holter System
GroupValue95% CI
Holter Device12
Detection of Atrioventricular Block Secondary · 24 hours

Number of patients with atrioventricular block (high-degree AV block, in which there is an interruption in the transmission of a heart beat from the atria to the ventricles, including those classified as 2nd degree AV block Mobitz type I and II, AV block 2:1 or complete AV block) detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device5
Conventional Holter System
GroupValue95% CI
Holter Device4
Detection of Heart Beat Pauses Secondary · 24 hours

Number of patients with heart beat pauses ≥ 2.5 seconds detected in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device7
Conventional Holter System
GroupValue95% CI
Holter Device11
Duration of the Holter Exam Secondary · 24 hours

Duration of the Holter exam in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device21.79± 1.40
Conventional Holter System
GroupValue95% CI
Holter Device21.74± 1.95
Mean Heart Rate Secondary · 24 hours

Mean heart rate measured in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device69.73± 12.10
Conventional Holter System
GroupValue95% CI
Holter Device70.67± 12.24
Maximum Heart Rate Secondary · 24 hours

Maximum heart rate measured in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device113.59± 23.17
Conventional Holter System
GroupValue95% CI
Holter Device116.30± 24.76
Minimum Heart Rate Secondary · 24 hours

Minimum heart rate measured in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device49.56± 9.83
Conventional Holter System
GroupValue95% CI
Holter Device49.17± 8.87
Atrial Ectopic Heart Beats Secondary · 24 hours

Total number of atrial ectopic heart beats measured in both Holter monitors

Innovative 3-lead Wireless Water Resistant Holter System
GroupValue95% CI
Holter Device717.09± 2323.94
Conventional Holter System
GroupValue95% CI
Holter Device723.46± 2223.27

Sponsor's own description

Holter monitoring is one of the most widely used diagnostic methods to detect cardiac arrhythmias. Newer Holter monitors may provide some advantages over the more traditional ones. This study will compare the findings of a Holter exam using an innovative 3-lead wireless water resistant device with a conventional device.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Cardiac Arrhythmia

Currently open trials in the same condition.

Other Hospital Israelita Albert Einstein trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04723355.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing