NCT04720755 is a NA clinical trial of Low-Intensity Extracorporeal Shock Wave Therapy in Erectile Dysfunction, sponsored by Hunter Holmes Mcguire Veteran Affairs Medical Center.

Who is sponsoring NCT04720755?

NCT04720755 is sponsored by Hunter Holmes Mcguire Veteran Affairs Medical Center.

What drugs are being tested in NCT04720755?

Interventions in NCT04720755: Low-Intensity Extracorporeal Shock Wave Therapy.

What condition does NCT04720755 study?

NCT04720755 studies Erectile Dysfunction.

Is NCT04720755 still recruiting?

NCT04720755 is currently completed. Last updated 26 October 2024.

Last reviewed 2024-10-26 · How we verify

NCT04720755

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Low Intensity Extracorporeal Shock Wave Therapy (Li-ESWT) for Erectile Dysfunction

Completed NA Last updated 26 October 2024

What this trial tests

NA trial testing Low-Intensity Extracorporeal Shock Wave Therapy in Erectile Dysfunction in 25 participants. Completed in 21 September 2023.

Timeline

1 March 2021

Primary endpoint
21 September 2023

21 September 2023

Quick facts

Lead sponsor	Hunter Holmes Mcguire Veteran Affairs Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	25
Start date	1 March 2021
Primary completion	21 September 2023
Estimated completion	21 September 2023
Sites	1 location across United States

Drugs / interventions tested

Low-Intensity Extracorporeal Shock Wave Therapy

Conditions studied

Erectile Dysfunction — all drugs for Erectile Dysfunction →

Sponsor

Hunter Holmes Mcguire Veteran Affairs Medical Center

Who can join

Adults 40 to 80, male only, with Erectile Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Low-intensity extracorporeal shock wave therapy (Li-ESWT) has shown promise as a novel treatment for erectile dysfunction (ED), though the the mechanism of action and optimal protocol for administration has not been well-established. The aim of this study is to assess for subjective and objective improvements in erectile function following treatment with Li-ESWT.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Lack of sustained improvements in erectile function following low-intensity extracorporeal shockwave therapy correlate with decreases in corporal brain-derived neurotropic factor: a pilot study and prospective clinical trial.
Coffey S, Nguyen V, Matthew AN, Kastelberg BS, et al · · 2025 · PMID 41583708 · DOI 10.1093/sexmed/qfaf107

Verify or expand the search:

Other recruiting trials for Erectile Dysfunction

Currently open trials in the same condition.

NCT07442396 — The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation · NA · recruiting
NCT07366970 — Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D? · NA · recruiting
NCT06960746 — Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response? · NA · recruiting
NCT06872866 — The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under · Phase 1 · recruiting
NCT06805513 — Actual Use Trial of Tadalafil 5 mg · Phase 3 · recruiting

Other Hunter Holmes Mcguire Veteran Affairs Medical Center trials

Trials by the same sponsor.

NCT06464952 — Microbiome Modulation With Prebiotics in PTSD and Cirrhosis · NA · recruiting
NCT06052176 — Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement · Phase 2 · recruiting
NCT06052150 — Oral Health In Cirrhosis of the Liver (ORACLE) · active not recruiting
NCT06110364 — Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions · Phase 3 · withdrawn
NCT05604274 — Longitudinal Monitoring of Stool Characteristics · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04720755 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hunter Holmes Mcguire Veteran Affairs Medical Center
Last refreshed: 26 October 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04720755.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing