Who is sponsoring NCT04719624?

NCT04719624 is sponsored by Orton Orthopaedic Hospital.

What drugs are being tested in NCT04719624?

Interventions in NCT04719624: Adaptos®-Si [0.5-1 mm] (bone grafting surgery), Adaptos®-Si [1-2 mm] (bone grafting surgery), Geistlich Bio-Oss (bone grafting surgery), Tooth extraction without bone graft material, Adaptos® (bone grafting surgery).

What condition does NCT04719624 study?

NCT04719624 studies Alveolar Ridge Preservation.

Is NCT04719624 still recruiting?

NCT04719624 is currently terminated. Last updated 2 November 2023.

Last reviewed 2023-11-02 · How we verify

NCT04719624

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Novel Porous Bioceramic Material as a Bone Substitute

Terminated NA Last updated 2 November 2023

What this trial tests

NA trial testing Adaptos®-Si [0.5-1 mm] (bone grafting surgery) in Alveolar Ridge Preservation in 76 participants. Terminated before completion.

Timeline

1 June 2021

Primary endpoint
27 January 2023

27 January 2023

Quick facts

Lead sponsor	Orton Orthopaedic Hospital
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	76
Start date	1 June 2021
Primary completion	27 January 2023
Estimated completion	27 January 2023
Sites	1 location across Finland

Drugs / interventions tested

Adaptos®-Si [0.5-1 mm] (bone grafting surgery)
Adaptos®-Si [1-2 mm] (bone grafting surgery)
Geistlich Bio-Oss (bone grafting surgery)
Tooth extraction without bone graft material
Adaptos® (bone grafting surgery)

Conditions studied

Alveolar Ridge Preservation — all drugs for Alveolar Ridge Preservation →

Sponsor

Orton Orthopaedic Hospital

Who can join

Adults 18 to 80, any sex, with Alveolar Ridge Preservation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to demonstrate that new synthetic bone graft bioceramic composites (Adaptos®-Si and Adaptos®, Biomendex Oy) are able to support the preservation of the alveolar ridge and to promote bone regeneration following dental extraction. New bone graft substitutes are compared with already existing treatment principles used following dental extraction. The primary hypothesis of the study is that Adaptos®-Si granules can reach a clinical outcome superior to that of dental socket left empty after extraction. Secondary aim is that new bioceramic composites can reach a clinical outcome non inferior to the active comparator of this study (Geistlisch Bio-Oss®).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Alveolar Ridge Preservation

Currently open trials in the same condition.

NCT07242313 — Comparison of Demineralized and Mineralized Dentin Grafts in Ridge Preservation · NA · recruiting
NCT07526129 — Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiograp · recruiting
NCT06827665 — Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation · Phase 1, PHASE2 · recruiting
NCT06784232 — Alveolar Ridge Preservation: Biologically-oriented Alveolar Ridge Preservation Vs Modified Periosteal Inhibition · active not recruiting
NCT06141239 — 2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone · NA · recruiting

Other Orton Orthopaedic Hospital trials

Trials by the same sponsor.

NCT06837025 — Fascial Manipulation in Cerebral Palsy Rehabilitation · NA · recruiting
NCT05450263 — Preventing Chronicity of Sub-acute Low Back Pain by Altering the Neural Emotional Response to Pain · NA · withdrawn
NCT05641857 — Lumbar Spine on MRI and Low Back Pain in Elite Cross-country Skiers · completed
NCT03904030 — Postoperative Rehabilitation After Knee Arthroplasty: Anti-Gravity Treadmill · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04719624 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Orton Orthopaedic Hospital
Last refreshed: 2 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04719624.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing