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NCT04715880
The Comparison of the Analgesic Efficacy and Hemodynamic Effects of Paravertebral Block Compared With Paravertebral and Intercostal Nerve Block for Thoracotomy in Adults.
NA trial testing Paravertebral block/Intercostal Block (PVB/ICB) group in Pain, Postoperative in 70 participants. Completed in 5 April 2021.
1 April 2021
Quick facts
| Lead sponsor | Aga Khan University Hospital, Pakistan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 70 |
| Start date | 15 February 2021 |
| Primary completion | 1 April 2021 |
| Estimated completion | 5 April 2021 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Paravertebral block/Intercostal Block (PVB/ICB) group
- Paravertebral Block (PVB) group
Conditions studied
- Pain, Postoperative — all drugs for Pain, Postoperative →
- Nerve Block — all drugs for Nerve Block →
- Thoracotomy — all drugs for Thoracotomy →
Sponsor
Aga Khan University Hospital, Pakistan
Who can join
Adults 18 to 70, any sex, with Pain, Postoperative or Nerve Block. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Thoracotomy is a surgical procedure associated with severe post operative pain during the first day of surgery and is responsible for prolonged hospital stay, patient dissatisfaction and delayed return to normal activities along with increased morbidity and mortality. Investigators intend to compare the efficacy of two analgesic interventions (continuous infusion of paravertebral block (PVB) after loading dose compared with intercostal nerve block and continuous infusion of PVB without loading dose) on postoperative thoracotomy pain. The results of this study will direct the investigators to find the best practice methods which will reduce the postoperative thoracotomy pain, the overall cost of pain management and length of patient's hospital stay.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The comparison of the analgesic efficacy of continuous paravertebral block alone compared with continuous paravertebral and intercostal nerve block for thoracotomy in adults: a randomized controlled trial.
Kumar S, Hameed M, Shehzad R, Samad K. · · 2023 · cited 2× · PMID 37747499 · DOI 10.1007/s00540-023-03255-8
Verify or expand the search:
- PubMed search for NCT04715880
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04715880 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aga Khan University Hospital, Pakistan
- Last refreshed: 2 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04715880.
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