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NCT04712630: NIPSAGRAFT
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
NA trial testing Non-incised papila surgical approach without grafting biomaterial in Periodontitis in 24 participants. Completed in 30 December 2020.
9 September 2020
Quick facts
| Lead sponsor | Universidad de Murcia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 9 September 2019 |
| Primary completion | 9 September 2020 |
| Estimated completion | 30 December 2020 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Non-incised papila surgical approach without grafting biomaterial
- Non-incised papila surgical approach with grafting biomaterial
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Periodontal Diseases — all drugs for Periodontal Diseases →
- Periodontal Pocket — all drugs for Periodontal Pocket →
- Periodontal Attachment Loss — all drugs for Periodontal Attachment Loss →
Sponsor
Universidad de Murcia — full company profile →
Who can join
18 and older, any sex, with Periodontitis or Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study compared the clinical outcomes of the non-incised papila surgical approach (NIPSA) alone and with grafting biomaterial.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Apical approach in periodontal reconstructive surgery with enamel matrix derivate and enamel matrix derivate plus bone substitutes: a randomized, controlled clinical trial.
Moreno Rodríguez JA, Ortiz Ruiz AJ. · · 2022 · cited 13× · PMID 34791548 · DOI 10.1007/s00784-021-04256-1
Verify or expand the search:
- PubMed search for NCT04712630
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Universidad de Murcia trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04712630 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de Murcia
- Last refreshed: 15 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04712630.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing