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NCT04712058
Same-day Antiretroviral Therapy With BIC/F/TAF
NA trial testing Bictegravir / Emtricitabine / Tenofovir Alafenamide Oral Tablet [Biktarvy] in HIV Infections in 200 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 200 |
| Start date | 20 January 2021 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 January 2023 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Bictegravir / Emtricitabine / Tenofovir Alafenamide Oral Tablet [Biktarvy] — full drug profile →
Conditions studied
- HIV Infections — all drugs for HIV Infections →
Sponsor
National Taiwan University Hospital
Who can join
20 and older, any sex, with HIV Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
WHO had recommened rapid ART initiation, defined as starting ART within 7 days or on the same day after HIV diagnosis, to improve HIV care continuum. Prior studies revealed that point-of-care diagnostic methods for the detection of HIV RNA can accelerate linkage to care and reduce anxiety. By shortening the interval between infectious disease physician referral, time-lag between screening and confirmatory tests, with the use of the newly developed point-of-care immunochromatographic confirmatory test, initiating a safe and potent antiretroviral therapy, BIC/F/TAF, on the same day of HIV confirmation will be feasible to improve linkage to care and to shorten the interval between HIV diagnosis and viral suppression.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy of same-day initiation of antiretroviral therapy with coformulated bictegravir, emtricitabine, and tenofovir alafenamide: Week 48 results of a single-arm, open-label, multicenter clinical trial.
Huang YC, Ko WC, Sun HY, Cheng SH, et al · · 2026 · PMID 41354205 · DOI 10.1016/j.ijid.2025.108284
Verify or expand the search:
- PubMed search for NCT04712058
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04712058 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 19 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04712058.
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