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NCT04710849

Relationship Between Plasma Metabolome and the Efficacy of Systemic Glucocorticoid in AECOPD

Status unknown Last updated 15 January 2021
What this trial tests

trial testing Serum metabolic markers in COPD in 100 participants. Status unknown.

Timeline
1 February 2021
Primary endpoint
1 February 2024
1 June 2024

Quick facts

Lead sponsorPeking University Third Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment100
Start date1 February 2021
Primary completion1 February 2024
Estimated completion1 June 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Peking University Third Hospital

Who can join

18 and older, any sex, with COPD or COPD Exacerbation Acute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of the patients with COPD. Guidelines have recommended systemic glucocorticoid as regular treatment. Recently, evidences have shown that systemic glucocorticoid cannot not be benefit to all of the patients with AECOPD. Thus the problem that how the clinicians can screen the patients who can benefit from systemic glucocorticoid needs to be solved urgently.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Rationale and design of REGULATE: an observational study protocol for relationship between plasma metabolome and the efficacy of systemic glucocorticoid in acute exacerbation of chronic obstructive pulmonary disease.
    Li QY, An ZY, Pan ZH, Qi RY. · · 2021 · cited 1× · PMID 34320980 · DOI 10.1186/s12890-021-01614-3

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Other recruiting trials for COPD

Currently open trials in the same condition.

Other Peking University Third Hospital trials

Trials by the same sponsor.

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Data sources for this page

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