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NCT04710693

Implementation of Optical Diagnosis of Diminutive Colorectal Polyps: DISCARD3 Study (Incorporating AI-DETECT)

Completed NA Last updated 22 December 2021
What this trial tests

NA trial testing CAD polyp-detection system in Colonic Polyp in 614 participants. Completed in 3 December 2021.

Timeline
14 February 2020
Primary endpoint
3 December 2021
3 December 2021

Quick facts

Lead sponsorLondon North West Healthcare NHS Trust
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposediagnostic
Enrollment614
Start date14 February 2020
Primary completion3 December 2021
Estimated completion3 December 2021
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

London North West Healthcare NHS Trust — full company profile →

Who can join

Adults 55 to 74, any sex, with Colonic Polyp. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective feasibility study. The aim of this work is to assess the acceptability and feasibility of optical diagnosis-led care in bowel cancer screening patients undergoing colonoscopy. This study will determine whether bowel cancer screening colonoscopists are able to consistently record and diagnose diminutive adenomas suitable for a resect and discard strategy allowing assignment of surveillance intervals according to Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) criteria. A practical quality assurance program around optical diagnosis will be introduced. The use of a CAD polyp-detection system will also be evaluated (AI-DETECT).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Implementation of optical diagnosis with a "resect and discard" strategy in clinical practice: DISCARD3 study.
    Ahmad A, Moorghen M, Wilson A, Stasinos I, et al · · 2022 · cited 23× · PMID 35724693 · DOI 10.1016/j.gie.2022.06.019

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Other recruiting trials for Colonic Polyp

Currently open trials in the same condition.

Other London North West Healthcare NHS Trust trials

Trials by the same sponsor.

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Data sources for this page

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