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NCT04708626
Epidemiology of Autoimmune Encephalitides and Paraneoplastic Neurological Syndromes in Sweden
trial testing Description and analysis in Autoimmune Encephalitis in 110 participants. Completed in 1 August 2022.
1 August 2022
Quick facts
| Lead sponsor | Uppsala University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 110 |
| Start date | 1 October 2019 |
| Primary completion | 1 August 2022 |
| Estimated completion | 1 August 2022 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Description and analysis
- Description and analysis
Conditions studied
- Autoimmune Encephalitis — all drugs for Autoimmune Encephalitis →
- Paraneoplastic Neurological Syndrome — all drugs for Paraneoplastic Neurological Syndrome →
Sponsor
Uppsala University
Who can join
Eligibility, any sex, with Autoimmune Encephalitis or Paraneoplastic Neurological Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Autoimmune encephalitis and paraneoplastic neurological syndromes are rare diseases caused by an abnormal immune response toward the nervous system. This can lead to life-threatening symptoms, but is in many cases treatable if a swift and correct diagnosis is made. Antibodies targeting neuronal proteins (i.e. "neuronal antibodies") can be detected in serum or cerebrospinal fluid (CSF) in about half of the patients suffering from these conditions. Although an important part of the diagnostical process of these conditions, diagnosis cannot be made only based on a positive antibody test, but the clinical findings have to be compatible as well. As these conditions are so rare, clinicians might struggle to interpret antibody test results. In this study the investigators aim to estimate the incidence rate of autoimmune encephalitides and paraneoplastic neurological syndromes in the Uppsala-Örebro health care region in Sweden between the years 2015 and 2019. Medical records from patients belonging to the Uppsala-Örebro health care region (a region in the middle of Sweden with a population of approximately 2.1 million), that tested positive for any neuronal antibody in serum or CSF will be studied to obtain clinical, laboratory and radiological data. This data will be used to ascertain if diagnostic criteria are fulfilled as well as to describe clinical characteristics and identifying possible comorbidities.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Medical Applications of Molecular Biotechnologies in the Context of Hashimoto's Thyroiditis.
Trovato M, Valenti A. · · 2023 · cited 1× · PMID 37371008 · DOI 10.3390/diagnostics13122114
Verify or expand the search:
- PubMed search for NCT04708626
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Description and analysis
Trials testing the same drug.
- NCT04339127 — Autoimmune Encephalitis With Anti-NMDA Receptor Antibodies Following Herpetic Encephalitis · unknown
- NCT04463550 — GFAP Auto-immunity : a French Cohort Study · unknown
Other recruiting trials for Autoimmune Encephalitis
Currently open trials in the same condition.
- NCT07477015 — Study of Pathogenic Mechanisms and Identification of Novel Autoantibodies in Autoimmune Encephalitis · recruiting
- NCT06753955 — Phase 1 Study of ART5803 Safety and PK After IVIG in Healthy Participants · Phase 1 · active not recruiting
- NCT06575153 — Phase 1 Study of ART5803 in Healthy Participants · Phase 1 · active not recruiting
- NCT06079294 — Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism · NA · recruiting
- NCT06432803 — Metabolic Imaging for Diagnosis and Prognostication of Autoimmune encephalitiS · active not recruiting
Other Uppsala University trials
Trials by the same sponsor.
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- NCT07352683 — Open TAP-block in Pediatric Abdominal Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04708626 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Uppsala University
- Last refreshed: 9 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04708626.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing