NCT04702958 is a clinical trial in Heart Failure, sponsored by Inova Health Care Services.

Who is sponsoring NCT04702958?

NCT04702958 is sponsored by Inova Health Care Services.

What condition does NCT04702958 study?

NCT04702958 studies Heart Failure.

Is NCT04702958 still recruiting?

NCT04702958 is currently completed. Last updated 10 October 2023.

Last reviewed 2023-10-10 · How we verify

NCT04702958

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TRANSFORM-HF Ancillary Mechanistic Study

Completed Last updated 10 October 2023

What this trial tests

trial in Heart Failure in 150 participants. Completed in 30 May 2023.

Timeline

10 December 2020

Primary endpoint
30 May 2023

30 May 2023

Quick facts

Lead sponsor	Inova Health Care Services
Status	Completed
Study type	OBSERVATIONAL
Enrollment	150
Start date	10 December 2020
Primary completion	30 May 2023
Estimated completion	30 May 2023
Sites	9 locations across United States

Conditions studied

Heart Failure — all drugs for Heart Failure →

Sponsor

Inova Health Care Services — full company profile →

Who can join

18 and older, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with heart failure are frequently treated with diuretics, including furosemide and torsemide, but it is not known if one is better than the other. The TRANSFORM-HF trial is studying if torsemide is superior than furosemide for reducing the endpoint of death or hospitalization, but is not designed to study why. This ancillary study seeks to measure proteins in the blood and urine to help explain the underlying mechanism for why patients who take one of these diuretics may have better outcomes than patients who take the other.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Lipocalin 2-not only a biomarker: a study of current literature and systematic findings of ongoing clinical trials.
Asaf S, Maqsood F, Jalil J, Sarfraz Z, et al · · 2023 · cited 38× · PMID 36529828 · DOI 10.1007/s12026-022-09352-2

Verify or expand the search:

Other recruiting trials for Heart Failure

Currently open trials in the same condition.

NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting

Other Inova Health Care Services trials

Trials by the same sponsor.

NCT06564207 — Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults · Phase 2 · not yet recruiting
NCT07167199 — Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery · NA · not yet recruiting
NCT07437339 — Volume Reduction for Open Fracture Irrigation · Phase 4 · recruiting
NCT07485322 — Burn Pit Exposure in Veterans: A Cancer Screening Pilot Study at the Inova Saville Cancer Screening & Prevention Center · NA · not yet recruiting
NCT07335224 — Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04702958 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Inova Health Care Services
Last refreshed: 10 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04702958.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing