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Different Noradrenaline Protocols in Post Spinal Hypotension in CS
The incidence of hypotension after spinal anesthesia is approximately 60% in parturients undergoing cesarean section. As a consequence of hypotension, nausea-vomiting, dyspnea and neurological deterioration in patients and low Apgar scores in newborns may occur. Therefore, there is an increasing interest to prevent maternal post spinal hypotension by using several drugs including noradrenaline given in different protocols to the patients undergoing spinal anesthesia for cesarean section. However, there is no conclusive answer to the question of which dosage is the best to prevent the maternal post spinal hypotension in literature. In this prospective randomized study, we aimed to compare different noradrenaline protocols for preventing maternal post spinal hypotension during elective cesarean delivery.
Details
| Lead sponsor | Ankara University |
|---|---|
| Phase | PHASE4 |
| Status | COMPLETED |
| Enrolment | 180 |
| Start date | Mon Feb 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Wed Dec 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Hypotension
- Cesarean Section
- Anesthesia, Spinal
Interventions
- Noradrenalin 10 microgram bolus
- Noradrenaline 5 microgram bolus
- Noradrenaline 0.1 microgram/kg/minute infusion
- Noradrenaline 0.05 microgram/kg/minute infusion
- Infusion dosage: 0.075 microgram/kg/minute infusion
- Spinal anesthesia
Countries
Turkey (Türkiye)