Last reviewed · How we verify
NCT04693871
Effect of Left Atrial Appendage Velocity on Left Atrial Structure and Function After Radiofrequency Ablation Combined With Left Atrial Appendage Occlusion
trial testing Transesophageal ultrasound in Left Atrial Appendage Velocity in 100 participants. Completed in 1 January 2021.
1 January 2021
Quick facts
| Lead sponsor | The Second Hospital of Hebei Medical University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 January 2020 |
| Primary completion | 1 January 2021 |
| Estimated completion | 1 January 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- Transesophageal ultrasound
Conditions studied
- Left Atrial Appendage Velocity — all drugs for Left Atrial Appendage Velocity →
- Left Atrial Structure — all drugs for Left Atrial Structure →
- Left Atrial Function — all drugs for Left Atrial Function →
Sponsor
The Second Hospital of Hebei Medical University
Who can join
Adults 18 to 80, any sex, with Left Atrial Appendage Velocity or Left Atrial Structure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Radiofrequency ablation of atrial fibrillation combined with left atrial appendage closure can not only improve symptoms in patients with non-valvular atrial fibrillation, but also prevent left atrial appendage thrombosis. The safety and effectiveness of left atrial appendage occlusion have been confirmed by randomized controlled trials and actual experience. Among patients with different left atrial appendage emptying speeds, there are limited studies on the structure and function of the left atrial appendage after LAA closure. In this study, patients with persistent nonvalvular atrial fibrillation were selected for radiofrequency ablation combined with LAA closure. The sinus rhythm was restored after the operation. According to the different emptying speed of the left atrial appendage, they were divided into a high-flow rate group and a low-flow rate group. The differences in the structure and function of the left atrium between the two groups were analyzed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04693871
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transesophageal ultrasound
Trials testing the same drug.
- NCT07002775 — Which Position Is Better For CPR In OHCA Patients? · NA · enrolling by invitation
Other The Second Hospital of Hebei Medical University trials
Trials by the same sponsor.
- NCT07117422 — Venetoclax-Decitabine in Untreated Elderly/Unfit AML · NA · recruiting
- NCT06248242 — Treatment of Acute Ischemic Stroke With Rt-PA Combined With Edaravone Dexborneol · Phase 4 · unknown
- NCT04524780 — Use of Intracardiac Echocardiography or Left Atrial Appendage Radiography to Guide Implantation of a Left Atrial Appenda · NA · unknown
- NCT04524741 — Use of Intracardiac Echocardiography or Left Atrial Appendage Radiography to Guide Implantation of a Left Atrial Appenda · NA · unknown
- NCT05930262 — Acupuncture Therapy Combined With Breathing Training for Patients With Stroke Complicated · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04693871 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Second Hospital of Hebei Medical University
- Last refreshed: 18 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04693871.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing