Who is sponsoring NCT04693728?

NCT04693728 is sponsored by Phoenix VA Health Care System.

What drugs are being tested in NCT04693728?

Interventions in NCT04693728: Resilient Intrinsic Self-Regulation Strategies in Extremes.

What condition does NCT04693728 study?

NCT04693728 studies Chronic Pain.

Is NCT04693728 still recruiting?

NCT04693728 is currently completed. Last updated 5 January 2021.

Last reviewed 2021-01-05 · How we verify

NCT04693728: RISE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Adaptive Strategies for Resilient Intrinsic Self-Regulation in Extremes (RISE)

Completed NA Last updated 5 January 2021

What this trial tests

NA trial testing Resilient Intrinsic Self-Regulation Strategies in Extremes in Chronic Pain in 88 participants. Completed in 1 October 2020.

Timeline

13 August 2014

Primary endpoint
30 October 2018

1 October 2020

Quick facts

Lead sponsor	Phoenix VA Health Care System
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	88
Start date	13 August 2014
Primary completion	30 October 2018
Estimated completion	1 October 2020
Sites	1 location across United States

Drugs / interventions tested

Resilient Intrinsic Self-Regulation Strategies in Extremes

Conditions studied

Chronic Pain — all drugs for Chronic Pain →

Sponsor

Phoenix VA Health Care System — full company profile →

Who can join

Adults 18 to 80, any sex, with Chronic Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to assess the efficacy of a resilience intervention in Veterans with chronic pain compared to wait list control.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Adaptive Homeostatic Strategies of Resilient Intrinsic Self-Regulation in Extremes (RISE): A Randomized Controlled Trial of a Novel Behavioral Treatment for Chronic Pain.
Kent M, Mardian AS, Regalado-Hustead ML, Gress-Smith JL, et al · · 2021 · cited 2× · PMID 33912102 · DOI 10.3389/fpsyg.2021.613341

Verify or expand the search:

Other recruiting trials for Chronic Pain

Currently open trials in the same condition.

NCT07491549 — The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity · NA · recruiting
NCT07425691 — SPACE for Youth With Chronic Pain · recruiting
NCT07103135 — Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling · Phase 1 · recruiting
NCT06219408 — CIH Stepped Care for Co-occurring Chronic Pain and PTSD · NA · recruiting
NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting

Other Phoenix VA Health Care System trials

Trials by the same sponsor.

NCT03330548 — Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04693728 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Phoenix VA Health Care System
Last refreshed: 5 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04693728.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing