NCT04690049

An Innovative Therapeutic Exercise Approach Based on Load Progression Criteria for the Management of Shoulder Impingement Syndrome: a Randomized Controlled Trial

Withdrawn NA Last updated 2 April 2026

What this trial tests

NA trial testing Neuromuscular resistance exercise program in Shoulder Impingement. Withdrawn.

Timeline

1 December 2025

Primary endpoint
1 August 2026

1 February 2027

Quick facts

Lead sponsor	University of Malaga
Phase	NA
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Start date	1 December 2025
Primary completion	1 August 2026
Estimated completion	1 February 2027

Drugs / interventions tested

• Neuromuscular resistance exercise program
• Control exercise program with elastic band

Conditions studied

• Shoulder Impingement — all drugs for Shoulder Impingement →
• Tendinopathy — all drugs for Tendinopathy →

Sponsor

University of Malaga

Who can join

18 and older, any sex, with Shoulder Impingement or Tendinopathy. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• Change from baseline in Function measured with Disability of the Arm, Shoulder and Hand (DASH)
  Time frame: 14 weeks
  Functional scores from Disability of the Arm, Shoulder and Hand (DASH) questionnaire. Score ranges from 0 (no disability) to 100 (most severe disability)
• Change from baseline in Function measured with Constant-Murley Score (CMS)
  Time frame: 14 weeks
  Functional scores from Constant-Murley Score (CMS) Constant-Murley score (CMS) is a 100-points scale: the higher the score, the higher the quality of the function.
• Change from baseline in Function measured with Upper Limb Functional Index (ULFI)
  Time frame: 14 weeks
  Functional scores from Upper Limb Functional Index (ULFI) Score ranges from 0 (no disability) to 25 (most severe disability)
• Change from baseline Painful Sensation
  Time frame: 14 weeks
  Pain scores from Visual Analogue Scale (VAS) Score ranges from 0 (no pain) to 10 (most severe pain)
• Change from baseline Range of motion (ROM)
  Time frame: 14 weeks
  Active shoulder joint ROM (flexion, extension, abduction, internal/external rotations) by goniometry
• Change from baseline Subacromial Space
  Time frame: 14 weeks
  Measurement of subacromial space by ultrasonography

Sponsor's own description

Upper limb tendinopathies, especially the so called "shoulder impingement syndrome", is a common injury among the population. Its management usually involves active treatments, being the therapeutic progressive exercise the most important and effective modality. However, whether a certain criterion is more appropriate than another when progressing the exercise program remains unclear. We propose a new program based on progressive exercises serving as a standard approach for the management of shoulder impingement syndrome.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.