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NCT04688372
Hospital COVID-19 Surge and Associated Mortality Risk
trial testing Surge Index in Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals in 144,116 participants. Completed in 15 February 2021.
15 February 2021
Quick facts
| Lead sponsor | National Institutes of Health Clinical Center (CC) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 144,116 |
| Start date | 1 October 2020 |
| Primary completion | 15 February 2021 |
| Estimated completion | 15 February 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Surge Index
Conditions studied
- Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals — all drugs for Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals →
Sponsor
National Institutes of Health Clinical Center (CC)
Who can join
18 and older, any sex, with Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A retrospective cohort study will be conducted using a large administrative database of U.S. hospitals to understand the volume-outcome relationship among patients hospitalized with COVID-19.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020.
Kadri SS, Sun J, Lawandi A, Strich JR, et al · · 2021 · cited 168× · PMID 34224257 · DOI 10.7326/m21-1213
Verify or expand the search:
- PubMed search for NCT04688372
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04688372 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institutes of Health Clinical Center (CC)
- Last refreshed: 6 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04688372.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing