NCT04688073

Effect of Muscle Damage After Downhill Running on Postprandial Lipids

Completed NA Last updated 29 December 2020

What this trial tests

NA trial testing Exercise in Nutritional and Metabolic Diseases in 9 participants. Completed in 1 July 2019.

Timeline

15 May 2019

Primary endpoint
1 July 2019

1 July 2019

Quick facts

Lead sponsor	National Taiwan Sport University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	prevention
Enrollment	9
Start date	15 May 2019
Primary completion	1 July 2019
Estimated completion	1 July 2019
Sites	1 location across Taiwan

Drugs / interventions tested

• Exercise
• Rest

Conditions studied

• Nutritional and Metabolic Diseases — all drugs for Nutritional and Metabolic Diseases →
• Lipemia — all drugs for Lipemia →

Sponsor

National Taiwan Sport University

Who can join

Adults 20 to 40, male only, with Nutritional and Metabolic Diseases or Lipemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

All participants underwent three experimental trials, namely downhill running (DR), level running (LR), and the control (CON) in a cross-over design. Each trial lasted for 2 days. The participants were fed the same breakfast and lunch on day 1 in each trial. The participants arrived at the laboratory at 18:00 on day 1 and ran on the treadmill at 60% VO2max (downhill and level surface trials) or rested (CON trial) for 30 min. Subsequently, they were fed a standardized dinner (A meal box containing chicken, vegetables, and rice, 692 kcal, with 50% energy from carbohydrate, 32% from fat, and 18% from protein) within 20 min.

The participants returned to the laboratory at 07:30 on day 2 after an overnight fast. After baseline blood and gas samples were collected, the participants were fed a high-fat meal that included cereal, white bread, whipping cream, cheese, and butter. The high-fat meal provided fat 1.2 g/kg (65% energy), carbohydrate 1.1 g/kg (27% energy), protein 0.33 g/kg (8% energy), and 16.5 kcal/kg.

A 10-mL blood sample was collected from a forearm vein into nonheparinized tubes before and immediately after exercise or rest on day 1. On day 2, postprandial blood samples were collected from forearm veins into nonheparinized tubes by using an indwelling venous needle and a three-way stopcock. A 10-mL blood sample was collected before (0 h) and 0.5, 1, 2, 3, 4, 5, and 6 h after the high-fat meal.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.