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NCT04686318

Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute Pyelonephritis

Completed Last updated 14 September 2022
What this trial tests

trial testing Biomarkers for acute pyelonephritis in Acute Pyelonephritis in 229 participants. Completed in 1 June 2022.

Timeline
1 March 2021
Primary endpoint
28 February 2022
1 June 2022

Quick facts

Lead sponsorUniversity of Southern Denmark
StatusCompleted
Study typeOBSERVATIONAL
Enrollment229
Start date1 March 2021
Primary completion28 February 2022
Estimated completion1 June 2022
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

University of Southern Denmark

Who can join

18 and older, any sex, with Acute Pyelonephritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of patients hospitalized with suspected acute pyelonephritis (APN).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Improved diagnostics of infectious diseases in emergency departments: a protocol of a multifaceted multicentre diagnostic study.
    Skjøt-Arkil H, Heltborg A, Lorentzen MH, Cartuliares MB, et al · · 2021 · cited 17× · PMID 34593497 · DOI 10.1136/bmjopen-2021-049606
  2. Prediction of infection in the emergency department-a machine learning model.
    Søgaard SN, Skjøt-Arkil H, Mogensen CB, Rosenvinge FS, et al · · 2026 · PMID 42147041 · DOI 10.3389/frai.2026.1812692

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Other University of Southern Denmark trials

Trials by the same sponsor.

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Data sources for this page

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