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NCT04679259
Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery
NA trial testing Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood in Postoperative Cognitive Dysfunction in 82 participants. Completed in 29 October 2025.
22 October 2025
Quick facts
| Lead sponsor | SMG-SNU Boramae Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 82 |
| Start date | 6 January 2021 |
| Primary completion | 22 October 2025 |
| Estimated completion | 29 October 2025 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood
- Neurocognitive test
- Assessment of delirium
Conditions studied
- Postoperative Cognitive Dysfunction — all drugs for Postoperative Cognitive Dysfunction →
Sponsor
SMG-SNU Boramae Medical Center
Who can join
55 and older, any sex, with Postoperative Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Delayed neurocognitive recovery is defined as a cognitive decline arising after surgery. In the present study, the authors evaluate the level of D-Amino Acid Oxidase, D-serine and Serine racemase in blood as an indicator of delayed neurocognitive recovery after cardiac surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04679259
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Postoperative Cognitive Dysfunction
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Other SMG-SNU Boramae Medical Center trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04679259 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by SMG-SNU Boramae Medical Center
- Last refreshed: 20 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04679259.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing